T cells bearing the gamma delta antigen receptor (gamma delta T cells) can constitute up to 50 percent of T cells in the peripheral blood and lymphoid organs of young cattle. We present data showing that gamma delta T cells are involved in immune responses against Theileria parva. Gamma delta T c...
Daubenberger, C.A.
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Taracha, E.L.N.
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Gaidulis, L.
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Davis, W.C.
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McKeever, Declan J.
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[Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva]
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Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva
Initial laboratory trials of an experimental subunit vaccine against Theileria parva based on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors may have an i...
Ballingall, K.T.
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Luyai, A.
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Rowlands, G.J.
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Sales, J.
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Musoke, A.J.
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Morzaria, S.P.
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McKeever, Declan J.
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[Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen]
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Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen
Theileria parva, an obligate intracellular protozoan parasite of cattle, causes East Coast fever, a fatal, lymphoproliferative disease, endemic in large areas of East and Central Africa. The mammalian-infective sporozoites of T. parva mature within the salivary glands of the ixodid tick Rhipiceph...
Wells, C.W.
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Awino, Elias
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McKeever, Declan J.
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[Theileria parva sporozoite invasion and development within bovine dendritic cells]
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Theileria parva sporozoite invasion and development within bovine dendritic cells