Descubre y comparte nuestro conocimiento público

Se han encontrado 10 recursos

Resultados de búsqueda

Goddeeris, B.M.Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[East Coast Fever (Theileria parva). Cell-mediated immunity and protection]East Coast Fever (Theileria parva). Cell-mediated immunity and protection

The main aim of this meeting was to review those developments in the fields of immunology and immunoparasitology that have relevance to the development of vaccination strategies for ECF and trypanosomiasis. Of relevance to the control of ECF were recent developments in the elucidation of events t...


McKeever, Declan J.[Novel immunization strategies against protozoan parasites. Proceedings of a workshop]Novel immunization strategies against protozoan parasites. Proceedings of a workshop

Theileria parva is the causal agent of East Coast fever (ECF), a fatal disease of cattle characterized by pyrexia, transient lymphadenopathy and panleukopenia. We have evaluated monoclonal antibodies (mAb) against three distinct antigens (p67, PIM and p32) of the parasite as immunohistological re...


Honda, Y.Matsubara, Y.Morzaria, S.P.McKeever, Declan J.[Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes]Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes

Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understandin...


McKeever, Declan J.Taracha, E.L.N.Morrison, W. IvanMusoke, A.J.Morzaria, S.P.[Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies]Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies

Initial laboratory trials of an experimental subunit vaccine against Theileria parva based on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors may have an i...


Ballingall, K.T.Luyai, A.Rowlands, G.J.Sales, J.Musoke, A.J.Morzaria, S.P.McKeever, Declan J.[Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen]Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen
McKeever, Declan J.[Progress towards a vaccine against Theileria parva: Relevance for heartwater research]Progress towards a vaccine against Theileria parva: Relevance for heartwater research

The Development of a recombinant Theileria parva vaccine is discussed under the following headings: mechanisms of protection against ECF [East Coast fever]; cloning and expression of p67; immunization and challenge of cattle; interpretation of immunization and challenge data.


Musoke, A.J.McKeever, Declan J.Morzaria, S.P.Nkonge, C.Nene, Vishvanath[A recombinant vaccine for Theileria parva]A recombinant vaccine for Theileria parva
Nene, VishvanathBishop, Richard P.Dolan, T.T.McKeever, Declan J.Ole-MoiYoi, O.K.Morzaria, S.P.Musoke, A.J.Shaw, M.K.Toye, Philip G.Young, A.S.[Theileria parva: current status]Theileria parva: current status

Theileria parva, a protozoan parasite of cattle, causes a disease called East Coast fever. The disease is of economic importance because it causes high morbidity and mortality and limits the development of the cattle industry. This paper highlights the experiences with immunization against Theile...


Musoke, A.J.McKeever, Declan J.Morzaria, S.P.Nkonge, C.Nene, Vishvanath[Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen]Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen

Selecciona los documentos para visualizarlos

Nombre del archivo Ver recurso