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T cells bearing the gamma delta antigen receptor (gamma delta T cells) can constitute up to 50 percent of T cells in the peripheral blood and lymphoid organs of young cattle. We present data showing that gamma delta T cells are involved in immune responses against Theileria parva. Gamma delta T c...


Daubenberger, C.A.Taracha, E.L.N.Gaidulis, L.Davis, W.C.McKeever, Declan J.[Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva]Bovine gamma delta T cell responses to the intracellular protozoan parasite Theileria parva

The main aim of this meeting was to review those developments in the fields of immunology and immunoparasitology that have relevance to the development of vaccination strategies for ECF and trypanosomiasis. Of relevance to the control of ECF were recent developments in the elucidation of events t...


McKeever, Declan J.[Novel immunization strategies against protozoan parasites. Proceedings of a workshop]Novel immunization strategies against protozoan parasites. Proceedings of a workshop

Initial laboratory trials of an experimental subunit vaccine against Theileria parva based on the 67-kDa major sporozoite surface antigen revealed a range of responses to challenge. We have analyzed convergence in seven sets of monozygotic twins which suggests that genetic factors may have an i...


Ballingall, K.T.Luyai, A.Rowlands, G.J.Sales, J.Musoke, A.J.Morzaria, S.P.McKeever, Declan J.[Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen]Bovine leukocyte antigen major histocompatibility complex class II DRB3*2703 and DRB3*1501 alleles are associated with variation in levels of protection against Theileria parva challenge following immunization with the sporozoite p67 antigen

Theileria parva, a tick-transmitted protozoan parasite, infects cattle in eastern, central and southern Africa, leading to an acute, usually fatal lymphoproliferative disorder known as East Coast fever (1). It has been shown that the protective immune response against T. parva is mediated by clas...


Daubenberger, C.A.Heussler, V.Gobright, E.I.Wijngaard, P.L.J.Clevers, H.C.Wells, C.Tsuji, N.Musoke, A.J.McKeever, Declan J.[Molecular characterisation of a cognate 70 kDa heat shock protein of the protozoan parasite Theileria parva]Molecular characterisation of a cognate 70 kDa heat shock protein of the protozoan parasite Theileria parva

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