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A mathematical description of the transmission dynamics of the tick-borne infection Cowdria ruminantium in commercial beef enterprises in Zimbabwe was used to consider the potential impact of a candidate vaccine to prevent heartwater. The important characteristics of the vaccine were (1) a delay ...


O'Callaghan, C.J.Medley, G.F.Peter, T.F.Mahan, S.M.Perry, Brian D.[Predicting the effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection)]Predicting the effect of vaccination on the transmission dynamics of heartwater (Cowdria ruminantium infection)

Heartwater, caused by the rickettsial organism Cowdria ruminantium, is a serious constraint to livestock development in much of sub-Saharan Africa. Traditionally, the disease has been controlled by the use of chemical acaricides to control the vector tick. The University of Florida/USAID-supporte...


Mukhebi, A.W.Chamboko, TafireyiO'Callaghan, C.J.Peter, T.F.Kruska, R.L.Medley, G.F.Mahan, S.M.Perry, Brian D.[An assessment of the economic impact of heartwater (Cowdria ruminantium infection) and its control in Zimbabwe]An assessment of the economic impact of heartwater (Cowdria ruminantium infection) and its control in Zimbabwe

The authors highlight the reliance on repeated natural infections by tickborne pathogens to maintain immunity in immunized herds. That incidence of clinical heartwater in cattle, caused by Cowdria ruminantium, is low while intensive acaricide use interrupts transmission of pathogens. Evidence is ...


Perry, Brian D.Chamboko, TafireyiMahan, S.M.Medley, G.F.Minjauw, B.O'Callaghan, C.J.Peter, T.F.[The economics of integrated tick and tick-borne disease control on commercial farms in Zimbabwe]The economics of integrated tick and tick-borne disease control on commercial farms in Zimbabwe

Haemonchosis is considered to be the most economically important gastrointestinal disease of small ruminants in the tropics and subtropics. However, chemical anthelmintics, which were the mainstay of control, have been compromised by a high prevalence of resistance worldwide. Copper oxide wire pa...


Spickett, A.Villiers, Etienne P. deBoomker, J.Githiori, J.B.Medley, G.F.Stenson, M.O.Waller, P.J.Calitz, F.J.Vatta, A.F.[Tactical treatment with copper oxide wire particles and symptomatic levamisole treatment using the FAMACHA© system in indigenous goats in South Africa]Tactical treatment with copper oxide wire particles and symptomatic levamisole treatment using the FAMACHA© system in indigenous goats in South Africa

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