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The indirect MAP 1B ELISA based on the recombinant MAP 1B fragment of the immunodominant MAP 1 protein of Ehrlichia ruminantium is considered to be the most sensitive and specific assay for the serodiagnosis of heartwater. In this study, we evaluated its reliability in detecting exposure to E....


Peter, T.F.O'Callaghan, C.J.Medley, G.F.Perry, Brian D.Semu, S.M.Mahan, S.M.[Population-based evaluation of the Ehrlichia ruminantium MAP 1B indirect ELISA]Population-based evaluation of the Ehrlichia ruminantium MAP 1B indirect ELISA

The high prevalence of resistance of Haemonchus contortus to all major anthelmintic groups has prompted investigations into alternative control methods in South Africa, including the use of copper oxide wire particle (COWP) boluses. To assess the efficacy of COWP against H. contortus in indigenou...


Vatta, A.F.Waller, P.J.Githiori, J.B.Medley, G.F.[The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles]The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles

As part of a series of studies associated with the development of improved vaccines for heartwater (a tick-borne disease of ruminant livestock caused by Cowdria ruminantium), field surveys were carried out to assess losses associated with the disease and the costs associated with controlling it i...


Chamboko, TafireyiMukhebi, A.W.Callaghan, C.J.O.Peter, T.F.Kruska, R.L.Medley, G.F.Mahan, S.M.Perry, Brian D.[The control of heartwater on large-scale commercial and smallholder farms in Zimbabwe]The control of heartwater on large-scale commercial and smallholder farms in Zimbabwe

Adult Amblyomma hebraeum ticks, the principle vector of heartwater (cowdriosis) of domestic ruminants in southern Africa, were collected in pheromone traps placed in Kruger National Park, an exclusively wildlife sanctuary in South Africa. These ticks transmitted Cowdria ruminantium, the rickettsi...


Peter, T.F.Bryson, N.R.Perry, Brian D.O'Callaghan, C.J.Medley, G.F.Smith, G.E.Mlambo, G.Horak, I.G.Burridge, M.J.Mahan, S.M.[Cowdria ruminantium infection in ticks in the Kruger National Park]Cowdria ruminantium infection in ticks in the Kruger National Park

Haemonchosis is considered to be the most economically important gastrointestinal disease of small ruminants in the tropics and subtropics. However, chemical anthelmintics, which were the mainstay of control, have been compromised by a high prevalence of resistance worldwide. Copper oxide wire pa...


Spickett, A.Villiers, Etienne P. deBoomker, J.Githiori, J.B.Medley, G.F.Stenson, M.O.Waller, P.J.Calitz, F.J.Vatta, A.F.[Tactical treatment with copper oxide wire particles and symptomatic levamisole treatment using the FAMACHA© system in indigenous goats in South Africa]Tactical treatment with copper oxide wire particles and symptomatic levamisole treatment using the FAMACHA© system in indigenous goats in South Africa

A study was conducted to examine the duration of anthelmintic effect of copper oxide wire particles (COWP) in grazing goats, as data for the persistence of efficacy of COWP in this host species is limited. Forty-eight indigenous male goats were infected naturally by grazing them on Haemonchus con...


Vatta, A.F.Waller, P.J.Githiori, J.B.Medley, G.F.[Persistence of the efficacy of copper oxide wire particles against Haemonchus contortus in grazing South African goats]Persistence of the efficacy of copper oxide wire particles against Haemonchus contortus in grazing South African goats

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