Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...
Olila, D.
,
McDermott, John J.
,
Eisler, M.C.
,
Mitema, E.S.
,
Patzelt, R.J.
,
Clausen, P.H.
,
Poetzsch, C.J.
,
Zessin, K.H.
,
Mehlitz, D.
,
Peregrine, A.S.
,
[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]
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Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda
Four Trypanosoma (T.) congolense reference clones with known isometamidium sensitivity and 16 T. congolense stocks from cattle in Kenedougou in south-western Burkina Faso, an area with known history of drug resistance, were characterised with the standard mouse test (SMT) and the drug incubatio...
Knoppe, T.N.
,
Bauer, B.
,
McDermott, John J.
,
Peregrine, A.S.
,
Mehlitz, D.
,
Clausen, P.H.
,
[Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test]
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Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test
Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...
Eisler, M.C.
,
Brandt, J.
,
Bauer, B.
,
Clausen, P.H.
,
Delespaux, V.
,
Holmes, P.H.
,
Ilemobade, A.
,
Machila, N.
,
Mbwambo, H.
,
McDermott, John J.
,
Mehlitz, D.
,
Murilla, G.
,
Ndung'u, J.M.
,
Peregrine, A.S.
,
Sidibe, I.
,
Sinyangwe, L.
,
Geerts, S.
,
[Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle]
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Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle
The aim of this study was to assess, whether polymerase chain reaction (PCR) allows sensitive screening of treatment failure suspicions in areas, where drug resistance against African animal trypanosomosis (AAT) appears to be a problem. PCR was used to detect trypanosome infections prior to, 14 ...
Gall, Y.
,
Woitag, T.
,
Bauer, B.
,
Sidibe, I.
,
McDermott, John J.
,
Mehlitz, D.
,
Clausen, P.H.
,
[Trypanocidal failure suggested by PCR results in cattle field samples]
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Trypanocidal failure suggested by PCR results in cattle field samples
Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...
Gall, Y.
,
Woitag, J.
,
Bauer, B.
,
Sidibe, I.
,
McDermott, John J.
,
Eisler, M.C.
,
Mehlitz, D.
,
Clausen, P.H.
,
[Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods]
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Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods