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Four Trypanosoma (T.) congolense reference clones with known isometamidium sensitivity and 16 T. congolense stocks from cattle in Kenedougou in south-western Burkina Faso, an area with known history of drug resistance, were characterised with the standard mouse test (SMT) and the drug incubatio...


Knoppe, T.N.Bauer, B.McDermott, John J.Peregrine, A.S.Mehlitz, D.Clausen, P.H.[Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test]Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test

In a cross-sectional study carried out in June 1994, 486 cattle from 50 randomly selected dairy farms in the vicinity of Kampala, Uganda, were examined for trypanosome infections. The trypanosome prevalence (either positive with the haematocrit centrifugation technique [HCT] and/or the mini-anion...


Clausen, P.H.Schares, G.Patzelt, R.J.Poetzsch, C.J.Scheer, A.Kakaire, D.Olila, D.Peregrine, A.S.McDermott, John J.Mehlitz, D.[PCR and DNA-probe hybridization to assess the efficacy of therapeutic and prophylactic isometamidium treatment in Trypanosoma spp. - infected dairy cattle in peri-urban Kampala, Uganda]PCR and DNA-probe hybridization to assess the efficacy of therapeutic and prophylactic isometamidium treatment in Trypanosoma spp. - infected dairy cattle in peri-urban Kampala, Uganda

Drug resistant trypanosome infections in livestock have been Reported from 13 sub-Saharan countries so far, in eight of which multiple resistance occurs. Since new trypanocides are unlikely to appear on the market in the near future, information about the occurrence, extent and impact of drug res...


Gall, Y.Woitag, J.Bauer, B.Sidibe, I.McDermott, John J.Eisler, M.C.Mehlitz, D.Clausen, P.H.[Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods]Detection of trypanocide failure in cattle: Diagnostic potential of PCR compared to parasitological methods

Trypanosomosis is an endemic disease in cattle in Mukono District in south eastern Uganda. A multi-disciplinary project was formulated in order to better understand the infection dynamics, and drug sensitivities, of the trypanosome parasites prevalent in Mukono, and also to assess the economic im...


Laker, C.D.Mukhebi, A.W.McDermott, John J.Patzelt, R.J.Potsch, C.Opuda-Asibo, J.Mehlitz, D.[Assessment of financial costs for the control of bovine trypanosomiasis in Mukono county, Uganda]Assessment of financial costs for the control of bovine trypanosomiasis in Mukono county, Uganda

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