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Abstract Background As in many different areas of science and technology, most important problems in bioinformatics rely on the proper development and assessment of binary classifiers. A generalized assessment of the performance of binary classifiers...


Vergara, Ismael A.Norambuena Arenas, Tomás.Ferrada, Evandro.Slater Morales, Alex William.Melo Ledermann, Francisco Javier.[StAR: a simple tool for the statistical comparison of ROC curves]StAR: a simple tool for the statistical comparison of ROC curves

Abstract Background The clawed African frog Xenopus laevis has been one of the main vertebrate models for studies in developmental biology. However, for genetic studies, Xenopus tropicalis has been the experimental model of choice because it shorter ...


Riadi, Gonzalo.Melo Ledermann, Francisco Javier.[Towards the bridging of molecular genetics data across Xenopus species]Towards the bridging of molecular genetics data across Xenopus species

Abstract Background The total number of known three-dimensional protein structures is rapidly increasing. Consequently, the need for fast structural search against complete databases without a significant loss of accuracy is increasingly demanding. R...


Gutiérrez, Fernando I.Rodríguez Valenzuela, Felipe.Ibarra, Ignacio L.Melo Ledermann, Francisco Javier.Devos, Damien P.[Efficient and automated large-scale detection of structural relationships in proteins with a flexible aligner]Efficient and automated large-scale detection of structural relationships in proteins with a flexible aligner

Capriotti, E.Norambuena Arenas, Tomás.Melo Ledermann, Francisco Javier.[All-atom knowledge-based potential for RNA structure prediction and assessment]All-atom knowledge-based potential for RNA structure prediction and assessment

Slater Morales, Alex WilliamMelo Ledermann, Francisco Javier.[Towards the development of standardized methods for comparison, ranking and evaluation of structure alignments]Towards the development of standardized methods for comparison, ranking and evaluation of structure alignments

Vergara Saavedra, Ismael Antonio.Melo Ledermann, Francisco Javier.[Autosomal STR allele frequencies for the CODIS system from a large random population sample in Chile]Autosomal STR allele frequencies for the CODIS system from a large random population sample in Chile

Gazitúa Zavala, María Consuelo.Slater Morales, Alex William.Melo Ledermann, Francisco Javier.[Novel alpha-ketoglutarate dioxygenase tfdA-related genes are found in soil DNA after exposure to phenoxyalkanoic herbicides]Novel alpha-ketoglutarate dioxygenase tfdA-related genes are found in soil DNA after exposure to phenoxyalkanoic herbicides

Faunes Quinteros, Fernando Emerson.Melo Ledermann, Francisco Javier.Larraín Correa, Juan Agustín.[Characterization of small RNAs in Xenopus tropicalis gastrulae]Characterization of small RNAs in Xenopus tropicalis gastrulae

Benadof, D.Melo Ledermann, Francisco Javier.[A new multiplex PCR assay for the simultaneous detection of vancomycin-resistant enterococci from rectal swabs]A new multiplex PCR assay for the simultaneous detection of vancomycin-resistant enterococci from rectal swabs

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