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This paper reports the results of a genome-wide search for quantitative trait loci (QTL) influencing immunological responses to infection with the gastro-intestinal nematode parasite Heligmosomoides polygyrus in an F2 population created by crossing the resistant SWR and the susceptible CBA inbr...


Menge, D.M.Behnke, J.M.Lowe, A.Gibson, John P.Iraqi, F.A.Baker, R.L.Wakelin, D.[Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice]Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice

Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...


Iraqi, F.A.Behnke, J.M.Menge, D.M.Lowe, A.M.Teale, A.J.Gibson, John P.Baker, L.R.Wakelin, D.R.[Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice]Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice

Genome-wide quantitative trait locus (QTL) mapping was used to evaluate the genetic basis of resistance to Helgmosomides polygyrus in an F2 cross of SWR and CBA mouse strains that are resistant and susceptible, respectively, to infection. 25 significant QTL affecting at least one of the resistanc...


Menge, D.M.Behnke, J.M.Iraqi, F.A.Lowe, A.Teale, A.J.Gibson, John P.Wakelin, D.Baker, R.L.[Quantitative trait loci for resistance to gastro-intestinal nematode infections in mice]Quantitative trait loci for resistance to gastro-intestinal nematode infections in mice

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