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The mechanisms whereby trypanotolerant N'Dama cattle control infection with Trypanosoma congolense are unknown. Previous studies have suggested that the monocytes of N'Dama cattle are more highly activated during infection than those of trypanosus ceptible Boan cattle. However, we have recently r...
Culture of bone marrow precursor cells with cytokines, including granulocyte - macrophage colony-stimulating factor (GM-CSF), interleukin-4 (IL-4) and the tyrosine kinase receptor binding proteins Flt-3 ligand (Flt3L) and stem-cell factor (SCF), has previously been shown, in both mouse and human,...
Integration of information from household surveys and data on land-cover changes derived from remote sensing helps to understand the causes and processes of land-use/land-cover changes. A household survey covering 552 households in 33 villages was carried out in the East Province of Cameroon. Thi...
The Amazon is the largest tropical forest area on earth, and has been undergoing rapid deforestation for the last four decades. In the Brazilian Amazon, large-scale pasture for cattle ranching and soybean production are the main land uses, leading to a yearly deforestation rate of 0.5%. These con...
African trypanosomes are important pathogens of both humans and livestock. We investigated the association of cytokine responses with disease susceptibility in Trypanosoma congolense-infected cattle. Changes in interleukin (IL)-1 beta, IL-2, IL-4, IL-5, IL-6, IL-12 p40, tumor necrosis factor-alph...
The cDNA coding for the soluble form of bovine stem cell factor (boSCF-Ala-105) was cloned and recombinant protein was produced in bacteria as a histidine tagged-protein. The protein was purified from the inclusion bodies in one step by metal chelation chromatography under denaturing conditions. ...
Trypanosomosis is the most economically important disease constraint to livestock productivity in sub-Saharan Africa and has significant negative impact in other parts of the world. Livestock are an integral component of farming systems and thus contribute significantly to food and economic secur...
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