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Infection of livestock with African trypanosomes leads to haematological changes such as anaemia and pancytopenia and to immune defects, including suppression of T-cell responsiveness and an excessive increase in the CD5+ B-cell population in blood and spleen. It has been shown that certain breed...


Mertens, B.Gaidulis, L.Mwangi, S.Suliman, H.Taylor, K.A.[Development of bovine-specific cytokine reagents at ILRAD]Development of bovine-specific cytokine reagents at ILRAD

T-cell-mediated immune responses to defined antigens of Trypanosoma congolense were measured in cattle undergoing primary infection. The antigens used were the variable surface glycoprotein and two invariant antigens, a 33-kDa cysteine protease (congopain) and a recombinant form of a 69-kDa heat-...


Lutje, V.Mertens, B.Boulange, A.F.Williams, D.J.L.Authié, E.[Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle]Trypanosoma congolense: Proliferative responses and interleukin production in lymph node cells of infected cattle

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