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Culture of bone marrow precursor cells with cytokines, including granulocyte - macrophage colony-stimulating factor (GM-CSF), interleukin-4 (IL-4) and the tyrosine kinase receptor binding proteins Flt-3 ligand (Flt3L) and stem-cell factor (SCF), has previously been shown, in both mouse and human,...


Hope, J.C.Werling, R.A.Collins, R.A.Mertens, B.Howard, C.J.[FLT-3 Ligand in combination with bovine Granulocyte-Macrophage colony-stimulating factor and interleukin-4, promotes the growth of bovine bone marrow derived dendritic cells]FLT-3 Ligand in combination with bovine Granulocyte-Macrophage colony-stimulating factor and interleukin-4, promotes the growth of bovine bone marrow derived dendritic cells

Trypanosomosis is the most economically important disease constraint to livestock productivity in sub-Saharan Africa and has significant negative impact in other parts of the world. Livestock are an integral component of farming systems and thus contribute significantly to food and economic secur...


Taylor, K.A.Mertens, B.[Immune responses of cattle to African trypanosomes: Protective or pathogenic?]Immune responses of cattle to African trypanosomes: Protective or pathogenic?

A bobine cDNA encoding erythropoietin (Epo) was isolated by polymerase chain reaction (PCR) amplification and screening of a bovine kidney cDNA library. The sequenced cDNA has a length of 1312 bp and an open reading frame that encodes a predicted 192-amino-acid (aa) protein, including a putative ...


Suliman, H.B.Majiwa, P.A.O.Feldman, B.F.Mertens, B.Logan-Henfrey, L.L.[Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues]Cloning of a cDNA encoding bovine erythropoietin and analysis of its transcription in selected tissues

The Development of vaccine against the African trypanosomiasis passes through the identification process of invariant component. This process targets the prevention of infection or diseases related to it. Immunity suppression in almost a universal feature of infection and represents probably an e...


Taylor, K.Mertens, B.Rocchi, M.Elson, L.[Immune suppression during bovine trypanosomosis]Immune suppression during bovine trypanosomosis

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