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Although immunodominance of CD8+ T-cell responses is a well-recognised feature of viral infections, its role in responses to more antigenically complex pathogens is less clear. In previous studies we have observed that CD8+ T-cell responses to Theileria parva exhibit different patterns of parasit...


MacHugh, Niall D.Connelley, T.Graham, S.P.Pelle, RogerFormisano, P.Taracha, E.L.N.Ellis, S.A.McKeever, Declan J.Burrells, A.Morrison, W. Ivan[CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity]CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity
Whitelaw, D.D.Moulton, J.E.Morrison, W. IvanMurray, M.[Central nervous system involvement in goats undergoing primary infections with Trypanosoma brucei and relapse infections after chemotherapy]Central nervous system involvement in goats undergoing primary infections with Trypanosoma brucei and relapse infections after chemotherapy
Howard, C.J.Morrison, W. IvanBrown, W.C.Naessens, JanSopp, P.[Demonstration of two allelic forms of the bovine T cell antigen Bo5 (CD5) and studies of their inheritance]Demonstration of two allelic forms of the bovine T cell antigen Bo5 (CD5) and studies of their inheritance
Morrison, W. IvanGoddeeris, M.[The role of the MHC in immunity of cattle to the protozoan parasite Theileria parva]The role of the MHC in immunity of cattle to the protozoan parasite Theileria parva
Goddeeris, B.M.Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[East Coast Fever (Theileria parva). Cell-mediated immunity and protection]East Coast Fever (Theileria parva). Cell-mediated immunity and protection

The protozoan parasite Theileria parva is the causal agent of an acute, usually fatal, disease of cattle characterized by widespread parasitism and destruction of cells of the lymphoid system. Animals which recover from infection are immune to challenge with the homologous stock of the parasite....


Morrison, W. IvanEmery, D.L.Teale, A.J.Goddeeris, B.M.[Protective immune responses in bovine theileriosis]Protective immune responses in bovine theileriosis
Morrison, W. IvanMacHugh, Niall D.Bensaid, A.M.Goddeeris, B.M.Teale, A.J.McKeever, Declan J.[A monoclonal antibody which reacts specifically with a population of bovine lymphocytes lacking B cell and T cell markers]A monoclonal antibody which reacts specifically with a population of bovine lymphocytes lacking B cell and T cell markers

Reviews prospects of vaccination against African trypanosomiasis, mentioning constraints in developing a vaccine, and current knowledge on the molecular biology of the trypanosome and on antigenic variation with respect to possible future vaccines. Describes possible regimes for immunological int...


Murray, M.Barry, J.D.Morrison, W. IvanWilliams, R.O.Hirumi, H.Rovis, L.[A review of the prospects for vaccination in African trypanosomiasis. Parts I, II]A review of the prospects for vaccination in African trypanosomiasis. Parts I, II

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...


Graham, S.P.Pelle, RogerVilliers, Etienne P. deYamage, M.Mwangi, D.M.Honda, Y.Ellis, S.A.MacHugh, Niall D.Morrison, W. IvanTaracha, E.L.N.[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva

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