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This review of the prospects for developing an immunization procedure against trypanosomiasis explores a number of promising avenues of research. Part I covers variable antigen types (VATs); metacyclic antigens; in vivo and in vitro attenuation; and molecular and genetic engineering. Part II, to ...


Murray, M.Barry, J.D.Morrison, W. IvanWilliams, R.O.Hirumi, H.Rovis, L.A.[A review of the prospects for vaccination in African trypanosomiasis. Part I]A review of the prospects for vaccination in African trypanosomiasis. Part I
Howard, C.J.Morrison, W. IvanBrown, W.C.Naessens, JanSopp, P.[Demonstration of two allelic forms of the bovine T cell antigen Bo5 (CD5) and studies of their inheritance]Demonstration of two allelic forms of the bovine T cell antigen Bo5 (CD5) and studies of their inheritance

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...


Graham, S.P.Pelle, RogerVilliers, Etienne P. deYamage, M.Mwangi, D.M.Honda, Y.Ellis, S.A.MacHugh, Niall D.Morrison, W. IvanTaracha, E.L.N.[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva
Wells, P.W.Emery, D.L.Hinson, C.A.Morrison, W. IvanMurray, M.[Immunization of cattle with variant-specific surface antigen of Trypanosoma brucei. The influence of different adjuvants]Immunization of cattle with variant-specific surface antigen of Trypanosoma brucei. The influence of different adjuvants
Clevers, H.C.MacHugh, Niall D.Bensaid, A.Dunlap, S.Baldwin, C.L.Kaushal, A.Iams, K.P.Howard, C.J.Morrison, W. Ivan[Identification of a bovine surface antigen uniquely expressed on CD4/CD8 negative TCR-gamma/delta positive T lymphocytes]Identification of a bovine surface antigen uniquely expressed on CD4/CD8 negative TCR-gamma/delta positive T lymphocytes
Davis, W.C.Grootenhuis, J.G.Magondu, J.Teale, A.J.Ellis, J.A.Morrison, W. Ivan[The use of flow microfluorimetry to identify monoclonal antibodies that cross-react with leucocyte differentiation antigens in domestic and wild ruminants]The use of flow microfluorimetry to identify monoclonal antibodies that cross-react with leucocyte differentiation antigens in domestic and wild ruminants
Baldwin, C.L.MacHugh, Niall D.Ellis, J.A.Naessens, JanNewson, J.Morrison, W. Ivan[Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: Tissue distribution and functional characteristics of the target antigens]Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: Tissue distribution and functional characteristics of the target antigens
Howard, C.J.Sopp, P.Parsons, K.R.McKeever, Declan J.Taracha, E.L.N.Jones, B.V.MacHugh, Niall D.Morrison, W. Ivan[Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45]Distinction of naive and memory BoCD4 lymphocytes in calves with a monoclonal antibody, CC76, to a restricted determinant of the bovine leukocyte-common antigen, CD45

In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...


Murray, M.Barry, J.D.Morrison, W. IvanWilliams, R.O.Hirumi, H.Rovis, L.A.[A review of the prospects for vaccination in African trypanosomiasis. Part II]A review of the prospects for vaccination in African trypanosomiasis. Part II
Parish, N.M.Morrison, W. IvanPearson, T.W.[Identification of an antigen specific to Trypanosoma congolense by using monoclonal antibodies]Identification of an antigen specific to Trypanosoma congolense by using monoclonal antibodies

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