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Journal Article 2009-03-15

Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva

Autor: Graham, S.P. Pelle, Roger Villiers, Etienne P. de Yamage, M. Mwangi, D.M. Honda, Y. Ellis, S.A. MacHugh, Niall D. Morrison, W. Ivan Taracha, E.L.N.

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...

Enlace original: https://cgspace.cgiar.org/handle/10568/32

Investigación en Agricultura

THEILERIA PARVA

ANTIGENS

TOXICITY

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Graham, S.P. , Pelle, Roger , Villiers, Etienne P. de , Yamage, M. , Mwangi, D.M. , Honda, Y. , Ellis, S.A. , MacHugh, Niall D. , Morrison, W. Ivan , Taracha, E.L.N. , [Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva] , Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva

Journal Article 1988

The MHC in bovine theileriosis

Autor: Morrison, W. Ivan Goddeeris, B.M. Teale, A.J.

This paper presents a summary of the current knowledge on the MHC restriction of Theileria specific cytotoxic T cell responses and indicated how MHC phenotype may influence the parasite strain specificity of the response. The data presented were derived from studies of the response in vivo as wel...

Enlace original: https://cgspace.cgiar.org/handle/10568/28222

Investigación en Agricultura

CATTLE

EAST COAST FEVER

BOVINE

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Morrison, W. Ivan , Goddeeris, B.M. , Teale, A.J. , [The MHC in bovine theileriosis] , The MHC in bovine theileriosis

Journal Article 2008

Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function

Autor: Houston, E.F. Taracha, E.L.N. Brackenbury, L. MacHugh, Niall D. McKeever, Declan J. Charleston, B. Morrison, W. Ivan

Theileria parva causes an acute lympho-proliferative disease in cattle, which can result in death of susceptible animals within 2-3 weeks of infection. Analyses of the cellular response in the lymph node draining the site of infection demonstrated an early T cell response, with the appearance of ...

Enlace original: https://cgspace.cgiar.org/handle/10568/28788

Investigación en Agricultura

THEILERIA PARVA

CATTLE

INFECTION

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Houston, E.F. , Taracha, E.L.N. , Brackenbury, L. , MacHugh, Niall D. , McKeever, Declan J. , Charleston, B. , Morrison, W. Ivan , [Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function] , Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function

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Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva

The MHC in bovine theileriosis

Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function