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The major histocompatibility complex (MHC) region contains many genes that are key regulators of both innate and adaptive immunity including the polymorphic MHCI and MHCII genes. Consequently, the characterisation of the repertoire of MHC genes is critical to understanding the variation that dete...


Vasoya, D.Law, A.Motta, P.Mingyan YuMuwonge, A.Cook, Elizabeth A.J.Xiaoying LiBryson, K.MacCallam, A.Sitt, T.Toye, Philip G.Bronsvoort, B.M. de C.Watson, MickMorrison, W. IvanConnelley, T.[Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing]Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations using next-generation sequencing

Analysis of cattle major histocompatibility complex (MHC) (BoLA) class I gene expression using serological and biochemical methods has demonstrated a high level of polymorphism. However, analysis of class I cDNA sequences has failed to produce conclusive evidence concerning the number and nature ...


Ellis, S.A.Holmes, E.C.Staines, K.A.Smith, K.B.Stear, M.J.McKeever, Declan J.MacHugh, Niall D.Morrison, W. Ivan[Variation in the number of expressed MHC genes in different cattle class I haplotypes]Variation in the number of expressed MHC genes in different cattle class I haplotypes
Morrison, W. IvanGoddeeris, M.Teale, A.J.Groocock, C.M.Kemp, Stephen J.Stagg, D.A.[Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity]Cytotoxic T cells elicited in cattle challenged with Theileria parva (Muguga): Evidence for restriction by class I MHC determinants and parasite strain specificity
Goddeeris, B.M.Toye, Philip G.Morrison, W. Ivan[Strain specificity of bovine Theileria parva-specific cytotoxic T cells is determined by the phenotype of the restricting class I MHC]Strain specificity of bovine Theileria parva-specific cytotoxic T cells is determined by the phenotype of the restricting class I MHC
Toye, Philip G.MacHugh, Niall D.Bensaid, A.M.Alberti, S.Teale, A.J.Morrison, W. Ivan[Transfection into mouse L cells of two serologically and functionally distinct bovine class I MHC molecules from a MHC-homozygoud animal: Evidence for a second class I locus in cattle]Transfection into mouse L cells of two serologically and functionally distinct bovine class I MHC molecules from a MHC-homozygoud animal: Evidence for a second class I locus in cattle
Goddeeris, B.M.Morrison, W. IvanTeale, A.J.[Generation of bovine cytotoxic cell lines, specific for cells infected with the protozoan parasite Theileria parva and restricted by products of the major histocompatibility complex]Generation of bovine cytotoxic cell lines, specific for cells infected with the protozoan parasite Theileria parva and restricted by products of the major histocompatibility complex

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