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This review of the prospects for developing an immunization procedure against trypanosomiasis explores a number of promising avenues of research. Part I covers variable antigen types (VATs); metacyclic antigens; in vivo and in vitro attenuation; and molecular and genetic engineering. Part II, to ...
In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...
This article attempts to evaluate the current state of knowledge on questions such as, to what extent is inheritance important and how is it influenced by environmental factors; what are the mechanisms underlying increased resistance; and how productive are these breeds under various levels of ch...
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