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Flach, E.J.Shambwana, I.Dolan, T.T.Kassim, A.Pedersen, H.Glass, M.Morzaria, S.P.[East Coast Fever immunization trials on Unguja Island, Zanzibar]East Coast Fever immunization trials on Unguja Island, Zanzibar

Mutugi, J.J.M.Young, A.S.Maritim, A.C.Ndungu, S.G.Linyonyi, A.Ngumi, P.N.Mining, S.K.Leitch, B.L.Stagg, D.A.Grootenhuis, J.G.Kariuki, D.P.Morzaria, S.P.Dolan, T.T.[Parasite stocks used for East Coast Fever immunization in Kenya]Parasite stocks used for East Coast Fever immunization in Kenya
Morzaria, S.P.Young, J.R.Spooner, P.R.Dolan, T.T.Bishop, Richard P.[Theileria parva: a restriction map and genetic recombination]Theileria parva: a restriction map and genetic recombination

The infection-and-treatment method (ITM) for immunization of cattle against East Coast fever has historically been used only on a limited scale because of logistical and policy constraints. Recent large-scale deployment among pastoralists in Tanzania has stimulated demand. Concurrently, a suite o...


Giulio, Giuseppe diLynen, GodelieveMorzaria, S.P.Oura, C.Bishop, Richard P.[Live immunization against East Coast fever - current status]Live immunization against East Coast fever - current status
Mukhebi, A.W.Morzaria, S.P.Perry, Brian D.Dolan, T.T.Norval, R.A.I.[Cost analysis of immunization of East Coast fever by the infection and treatment method]Cost analysis of immunization of East Coast fever by the infection and treatment method
Morzaria, S.P.Irvin, D.Dolan, T.T.[Immunization against East Coast Fever: Isolation and characterization of Theileria parva stocks from Unguja and Pemba for use in infection and treatment]Immunization against East Coast Fever: Isolation and characterization of Theileria parva stocks from Unguja and Pemba for use in infection and treatment

When compared with other Apicomplexan organisms. Theileria parva has an execptionally small, 10-12 Mbp. genome. There are only 4 chromosomes, each in the Mbp range, and a complete physical map, based on SfiI linking data, is available for each one. A number of genes and cDNAs have been mapped to ...


Nene, VishvanathMorzaria, S.P.Bishop, Richard P.[Organisation and informational content of the Theileria parva genome]Organisation and informational content of the Theileria parva genome

Theileria annulata and Theileria parva both poses a major surface antigen on the sporozoite stage of the life-cycle, called SPAG-1 and p67, respectively. In each case, these antigens are vaccine candidates and have been shown to induce a degree of homologous protection in earlier work. These anti...


Hall, R.Boulter, N.R.Brown, C.G.D.Wilkie, G.Kirvar, E.Nene, VishvanathMusoke, A.J.Glass, E.J.Morzaria, S.P.[Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva]Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva

The 'Muguga cocktail' which is composed of three Theileria parva stocks Muguga. Kiambu 5 and Serengeti-transformed has been used extensively for live vaccination against East Coast fever in cattle in eastern, central and southern Africa. Herein we describe the molecular characterization of the T....


Bishop, Richard P.Geysen, D.Spooner, P.R.Skilton, Robert A.Nene, VishvanathDolan, T.T.Morzaria, S.P.[Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle]Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle

Theileria parva is the causal agent of East Coast fever (ECF), a fatal disease of cattle characterized by pyrexia, transient lymphadenopathy and panleukopenia. We have evaluated monoclonal antibodies (mAb) against three distinct antigens (p67, PIM and p32) of the parasite as immunohistological re...


Honda, Y.Matsubara, Y.Morzaria, S.P.McKeever, Declan J.[Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes]Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes

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