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Salp15, a 15-kDa tick salivary gland protein, has several suppressive modes of activity against host immunity and plays a critical role in the transmission of Lyme disease spirochetes in Ixodes scapularis and Ixodes ricinus, major vectors of Lyme disease in North America and Western Europe. Salp1...


Murase, Y.Konnai, S.Yamada, S.Githaka, Naftaly W.Isezaki, M.Ito, T.Takano, A.Ando, S.Kawabata, H.Murata, S.Ohashi, K.[An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes]An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes

Ixodes ricinus immunosuppressor (Iris) is a tick salivary gland protein derived from I. ricinus. In this study, Iris homolog was identified in the salivary glands of Ixodes persulcatus, which is the specific vector of the Lyme disease agent in Japan. The homolog was named Ipis-1. To investigate t...


Toyomane, K.Konnai, S.Niwa, A.Githaka, Naftaly W.Isezaki, M.Yamada, S.Ito, T.Takano, A.Ando, S.Kawabata, H.Murata, S.Ohashi, K.[Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze]Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze

Piroplasms frequently infect domestic and wild carnivores. At present, there is limited information on the occurrence and molecular identity of these tick-borne parasites in wild felids in Kenya. In 2009, a pair of captive lions (Panthare leo) was diagnosed with suspected babesiosis and mineral d...


Githaka, Naftaly W.Konnai, S.Kariuki, E.Kanduma, E.G.Murata, S.Ohashi, K.[Molecular detection and characterisation of potentially new Babesia and Theileria species/variants in wild felids from Kenya]Molecular detection and characterisation of potentially new Babesia and Theileria species/variants in wild felids from Kenya

Recently, mortalities among giraffes, attributed to infection with unique species of piroplasms were reported in South Africa. Although haemoparasites are known to occur in giraffes of Kenya, the prevalence, genetic diversity and pathogenicity of these parasites has not been investigated. In thi...


Githaka, Naftaly W.Konnai, S.Skilton, Robert A.Kariuki, E.Kanduma, E.G.Murata, S.Ohashi, K.[Genotypic variations in field isolates of Theileria species infecting giraffes (Giraffa camelopardalis tippelskirchi and Giraffa camelopardalis reticulata) in Kenya]Genotypic variations in field isolates of Theileria species infecting giraffes (Giraffa camelopardalis tippelskirchi and Giraffa camelopardalis reticulata) in Kenya

Githaka, Naftaly W.Konnai, S.Bishop, Richard P.Odongo, D.Lekolool, I.Kariuki, E.Gakuya, F.Kamau, L.Isezaki, M.Murata, S.Ohashi, K.[Identification and sequence characterization of novel Theileria genotypes from the waterbuck (Kobus defassa) in a Theileria parva-endemic area in Kenya]Identification and sequence characterization of novel Theileria genotypes from the waterbuck (Kobus defassa) in a Theileria parva-endemic area in Kenya

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