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In an on-farm trial conducted amongst the Maasai pastoralists in Nkuruman and Nkineji areas of Kenya between April 2004 and August 2005 designed to evaluate the effectiveness of a synthetic tsetse repellent technology, we assessed the relationship between tsetse challenge and trypanosomosis incid...


Bett, Bernard K.Irungu, P.Nyamwaro, Sospeter S.Murilla, G.Kitala, P.Gathuma, J.Randolph, Thomas F.McDermott, John J.[Estimation of tsetse challenge and its relationship with trypanosomosis incidence in cattle kept under pastoral production systems in Kenya]Estimation of tsetse challenge and its relationship with trypanosomosis incidence in cattle kept under pastoral production systems in Kenya

Resistance to the drugs used to control African animal trypanosomosis is increasingly recognised as a constraint to livestock production in sub-Saharan Africa. The most commonly used tests for detection of trypanocidal drug resistance are tests using mice or ruminants, but these suffer from lack ...


Eisler, M.C.Brandt, J.Bauer, B.Clausen, P.H.Delespaux, V.Holmes, P.H.Ilemobade, A.Machila, N.Mbwambo, H.McDermott, John J.Mehlitz, D.Murilla, G.Ndung'u, J.M.Peregrine, A.S.Sidibe, I.Sinyangwe, L.Geerts, S.[Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle]Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle

Two enzyme-linked immunosorbent assays (ELISA) for the determination of homidium in serum of treated cattle have been developed and evaluated. One is a direct competition (Assay 1) and the other an indirect competition assay (Assay 2). Both assays are highly sensitive with a limit of detection of...


Murilla, G.Eisler, M.C.Peregrine, A.S.Ndung'u, J.M.Holmes, P.H.[Development and evaluation of an enzyme-linked immunosorbent assay (ELISA) for the determination of the trypanocidal drug homidium in serum of treated cattle]Development and evaluation of an enzyme-linked immunosorbent assay (ELISA) for the determination of the trypanocidal drug homidium in serum of treated cattle

Pharmacokinetic studies on the trypanocidal drug homidium bromide using a competitive enzyme immunoassay (detection limit 0.1 ng/mL) are reported for non-infected Friesian and Boran steers following treatment with homidium bromide at a dose of 1.0 mg/kg b.w. Following intravenous (i.v.) treatment...


Murilla, G.Holmes, P.H.Peregrine, A.S.Eisler, M.C.Ndung'u, J.M.[Some pharmacokinetic parameters of the trypanocidal drug homidium bromide in Friesian and Boran steers using an enzyme-linked immunosorbent assay (ELISA)]Some pharmacokinetic parameters of the trypanocidal drug homidium bromide in Friesian and Boran steers using an enzyme-linked immunosorbent assay (ELISA)

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