A Trypanosoma brucei brucei DNA repeat sequence termed NlaIII repeat (NR) was originally isolated from a multidrug-resistant field isolate CP547 [Jamnadass, R., 1995. Identification and characterisation of an extrachromosomal element from a multidrug-resistant isolate of T. brucei brucei, Ph.D. t...
Jamnadass, Ramni H.
,
Pelle, Roger
,
Pandit, P.
,
Ricard, B.
,
Murphy, N.B.
,
[Trypanosoma brucei: Composition, organisation, plasticity, and differential transcription of NlaIII repeat elements in drug-resistant and sensitive isolates]
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Trypanosoma brucei: Composition, organisation, plasticity, and differential transcription of NlaIII repeat elements in drug-resistant and sensitive isolates
Bloodstream forms (BSF) and procyclic culture forms (PCF) of African trypanosomes were incubated with a variety of lectins in vitro. Cessation of cell division and profound morphological changes were seen in procyclic forms but not in BSF after incubation with concanvavalin A (Con A). Wheat germ...
Pearson, T.W.
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Beecroft, R.P.
,
Welburn, S.C.
,
Ruepp, S.
,
Roditi, I.
,
Kuo-Yuan, H.
,
Englund, P.T.
,
Wells, C.W.
,
Murphy, N.B.
,
[The major cell surface glycoprotein procycline is a receptor for induction of a novel form of cell death in African trypanosomes in vitro]
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The major cell surface glycoprotein procycline is a receptor for induction of a novel form of cell death in African trypanosomes in vitro
A study was carried out to determine whether a drug-resistant trypanosome population could influence the survival of a drug-sensitive population in mixed infections in goats. To identify both populations during the course of a mixed infection, a system for distinguishing them was developed; using...
Burudi, E.M.E.
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Peregrine, A.S.
,
Majiwa, P.A.O.
,
Mbiuki, S.M.
,
Murphy, N.B.
,
[Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats]
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Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats
Leegwater, P.A.J.
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Strating, M.
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Murphy, N.B.
,
Kooy, R.F.
,
Vliet, P.C. van der
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Overdulve, J.P.
,
[The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame]
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The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame
Members of the genus Trypanosoma, within the order Kinetoplastida, are unicellular parasitic organisms which are a major threat to human health and livestock productivity in large areas of the developing world. Despite their relatively small genome size, these primitive organisms undergo complex ...
Murphy, N.B.
,
Pelle, Roger
,
[Rapid identification of differentially expressed genes in trypanosomes]
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Rapid identification of differentially expressed genes in trypanosomes
Osanya, A.
,
Pelle, Roger
,
Murphy, N.B.
,
[Rapid identification of differentially expressed genes in trypanosomes mRNA transcripts of African trypanosomes]
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Rapid identification of differentially expressed genes in trypanosomes mRNA transcripts of African trypanosomes
Murphy, N.B.
,
[Application of arbitrarily primed PCR fingerprinting to molecular studies on trypanosomes]
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Application of arbitrarily primed PCR fingerprinting to molecular studies on trypanosomes