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A Trypanosoma brucei brucei DNA repeat sequence termed NlaIII repeat (NR) was originally isolated from a multidrug-resistant field isolate CP547 [Jamnadass, R., 1995. Identification and characterisation of an extrachromosomal element from a multidrug-resistant isolate of T. brucei brucei, Ph.D. t...


Jamnadass, Ramni H.Pelle, RogerPandit, P.Ricard, B.Murphy, N.B.[Trypanosoma brucei: Composition, organisation, plasticity, and differential transcription of NlaIII repeat elements in drug-resistant and sensitive isolates]Trypanosoma brucei: Composition, organisation, plasticity, and differential transcription of NlaIII repeat elements in drug-resistant and sensitive isolates

Bloodstream forms (BSF) and procyclic culture forms (PCF) of African trypanosomes were incubated with a variety of lectins in vitro. Cessation of cell division and profound morphological changes were seen in procyclic forms but not in BSF after incubation with concanvavalin A (Con A). Wheat germ...


Pearson, T.W.Beecroft, R.P.Welburn, S.C.Ruepp, S.Roditi, I.Kuo-Yuan, H.Englund, P.T.Wells, C.W.Murphy, N.B.[The major cell surface glycoprotein procycline is a receptor for induction of a novel form of cell death in African trypanosomes in vitro]The major cell surface glycoprotein procycline is a receptor for induction of a novel form of cell death in African trypanosomes in vitro
Dirie, M.F.Murphy, N.B.Gardiner, Peter R.[DNA fingerprinting of Trypanosoma vivax isolates rapidly identifies intraspecific relationships]DNA fingerprinting of Trypanosoma vivax isolates rapidly identifies intraspecific relationships

A study was carried out to determine whether a drug-resistant trypanosome population could influence the survival of a drug-sensitive population in mixed infections in goats. To identify both populations during the course of a mixed infection, a system for distinguishing them was developed; using...


Burudi, E.M.E.Peregrine, A.S.Majiwa, P.A.O.Mbiuki, S.M.Murphy, N.B.[Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats]Response of diminazene-resistance and diminazene-susceptible Trypanosoma congolense to treatment with diminazene when occuring as a mixed infection in goats
Leegwater, P.A.J.Strating, M.Murphy, N.B.Kooy, R.F.Vliet, P.C. van derOverdulve, J.P.[The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame]The Trypanosoma brucei DNA polymerase alpha core subunit gene is developmentally regulated and linked to a constitutively expressed open reading frame

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