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Heterologous priming-boosting vaccination regimens involving priming with plasmid DNA antigen constructs and inoculating (boosting) with the same recombinant antigen expressed in replication-attenuated poxviruses have recently been demonstrated to induce immunity, based on CD4(+)- and CD8(+)-T-c...
The Development of a recombinant Theileria parva vaccine is discussed under the following headings: mechanisms of protection against ECF [East Coast fever]; cloning and expression of p67; immunization and challenge of cattle; interpretation of immunization and challenge data.
The classification of bovine immunoglobulins is similar to that of nonruminant mammals, namely IgM, IgA, IgG<sub>1, IgG<sub>2 and IgE. There are minimal differences between IgG<sub>1 and IgG<sub>2 in complement fixation, ability to mediate passive cutaneous anaphylaxis, phagocytosis of coated er...
An interview with Tony Musoke, chair of the External Advisory Committee for the Improved Vaccines of the Control of East Coast Fever in Cattle in Africa Project at an inception workshop held 27-29 Jan in Nairobi, Kenya.
Bovine theileriosis caused by Theileria parva continues to be a major economic problem in many parts of Eastern, Southern, and Central Africa. Due to the unsustainable nature or the present control method-using toxic acaricides to kill ticks - alternative control methods are being sought. Live va...
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