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Nantulya, V.M.Musoke, A.J.Moloo, S.K.Ngaira, J.M.[Analysis of the variable antigen composition of Trypanosoma brucei metacyclic trypanosomes using monoclonal antibodies]Analysis of the variable antigen composition of Trypanosoma brucei metacyclic trypanosomes using monoclonal antibodies

Vaccines based on recombinant Bm86 gut antigen from Boophilus microplus are a useful component of integrated control strategies against B. microplus infestations of cattle. The capacity of such vaccines to control heterologous infestations by two African tick species was investigated. The mean we...


Odongo, D.Kamau, L.Skilton, Robert A.Mwaura, S.Nitsch, C.Musoke, A.J.Taracha, E.A.Daubenberger, C.A.Bishop, Richard P.[Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus]Vaccination of cattle with TickGARD induces cross-reactive antibodies binding to conserved linear peptides of Bm86 homologues in Boophilus decoloratus

Previous studies using monoclonal antibody (mAb) 4C9 specific for a 32 kDa antigen (p32) of Theileria parva demonstrated expression of the antigen on the surface of the sporozoite, making it a potential antigen for sporozoite neutralization. A full-length cDNA encoding the major merozoite/piropla...


Skilton, Robert A.Musoke, A.J.Wells, C.W.Yagi, Y.Nene, VishvanathSpooner, P.R.Gachanja, J.Osaso, J.Bishop, Richard P.Morzaria, S.P.[A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies]A 32 kDa surface antigen of Theileria parva: Characterization and immunization studies
Toye, Philip G.Goddeeris, M.Iams, K.P.Musoke, A.J.Morrison, W. Ivan[Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva]Characterization of a polymorphic immunodominant molecule in sporozoites and schizonts of Theileria parva

Tumor necrosis factor alpha (Tnf) plays a pleiotropic role in murine malaria. Some investigations have correlated Tnf with hypothermia, hyperlactatemia, hypoglycemia, and a suppression of the erythropoietic response, although others have not. In this study, we have evaluated parasitemia, survival...


Hernández Valladares, M.Naessens, JanMusoke, A.J.Sekikawa, K.Rihet, P.Ole-MoiYoi, O.K.Busher, P.Iraqi, F.A.[Pathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ]Pathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ
Young, A.S.Morzaria, S.P.Dolan, T.T.Musoke, A.J.Perry, Brian D.[Prospects of improved control of tick-borne diseases in Africa]Prospects of improved control of tick-borne diseases in Africa
Rovis, L.Musoke, A.J.Moloo, S.K.[Immunization trials against trypanosomiasis using common antigens]Immunization trials against trypanosomiasis using common antigens
Rurangirwa, F.R.Musoke, A.J.Nantulya, V.M.Nkonge, C.Njuguna, L.Mushi, E.Z.Karstad, L.Grootenhuis, J.G.[Immune effector mechanisms involved in the control of parasitaemia in Trypanosoma brucei-infected wildebeest (Connochaetes taurinus)]Immune effector mechanisms involved in the control of parasitaemia in Trypanosoma brucei-infected wildebeest (Connochaetes taurinus)

Theileria parva, a tick-transmitted protozoan parasite related to Plasmodium spp., causes the disease East Coast fever, an acute and usually fatal lymphoproliferative disorder of cattle in Africa. Previous studies using sera from cattle that have survived infection identified a polymorphic immuno...


Toye, Philip G.Metzelaar, M.J.Wijngaard, P.L.J.Nene, VishvanathIams, K.P.Roose, J.Nyanjui, J.K.Gobright, E.I.Musoke, A.J.Clevers, H.C.[Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parva]Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parva
Nene, VishvanathIams, K.P.Gobright, E.I.Musoke, A.J.[Characterisation of the gene encoding a candidate vaccine antigen of Theileria parva sporozoites]Characterisation of the gene encoding a candidate vaccine antigen of Theileria parva sporozoites

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