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Pig production is one of the fastest growing livestock sectors. Development of this sector is hampered by rapidly increasing costs of fishmeal (FM), which is a common protein source in animal feeds. Here, we explored the potential of substituting FM with black soldier fly larval meal (BSFLM) on g...


Chia, S.Y.Tanga, C.M.Osuga, I.M.Alaru, A.O.Mwangi, D.M.Githinji, M.Subramanian, S.Fiaboe, K.K.M.Ekesi, S.Loon, J.J.A. vanDicke, M.[Effect of dietary replacement of fishmeal by insect meal on growth performance, blood profiles and economics of growing pigs in Kenya]Effect of dietary replacement of fishmeal by insect meal on growth performance, blood profiles and economics of growing pigs in Kenya

Immunity against the bovine protozoan parasite Theileria parva has previously been shown to be mediated through lysis of parasite-infected cells by MHC class I restricted CD8+ cytotoxic T lymphocytes. It is hypothesized that identification of CTL target schizont antigens will aid the development ...


Graham, S.P.Honda, Y.Pelle, RogerMwangi, D.M.Glew, E.J.Villiers, Etienne P. deShah, TushaarBishop, Richard P.Bruggen, P. van derNene, VishvanathTaracha, E.L.N.[A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology]A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology

Events occurring in the skin of sheep prior to development of Trypanosoma congolense-induced local skin reactions (chancres) were studied using electron microscopy. Three days after infection, few trypanosomes were present in the dermal collagen. However, these parasites were more abundant 5 days...


Mwangi, D.M.Hopkins, J.Luckins, A.G.[Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions]Trypanosoma congolense infection in sheep: Ultrastructural changes in the skin prior to development of local skin reactions

Ways of promoting integration of herbaceous forage legumes into a napier grass fodder system were evaluated with the aim of increasing forage quantity and quality on smallholder dairy farms in central Kenya. The herbaceous legumes Desmodium intortum cGreenleaf (ILRI 104), Macrotyloma axillare cAx...


Mwangi, D.M.Cadisch, GeorgThorpe, W.R.Giller, Ken E.[Harvesting management options for legumes intercropped in napier grass in the central highlands of Kenya]Harvesting management options for legumes intercropped in napier grass in the central highlands of Kenya

East Coast fever (ECF) is a highly fatal lymphoproliferative disease of cattle caused by Theileria parva, a tick-borne intracellular apicomplexan parasite. Parasite antigens that are targets of protective cytotoxic T lymphocyte (CTL) responses are required to formulate a sub-unit vaccine against ...


Akoolo, L.Pelle, RogerSaya, R.Awino, EliasNyanjui, J.Taracha, E.L.N.Kanyari, P.Mwangi, D.M.Graham, S.P.[Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle]Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle

Wanyoike, Francis N.Nyangaga, J.Kariuki, E.Mwangi, D.M.Wokabi, A.Kembe, M.Staal, Steven J.[The Kenyan cattle population: the need for better estimation methods]The Kenyan cattle population: the need for better estimation methods

Forage legumes have been introduced to farmers in Central Kenya between 1980 and 2002 through various Institutional and Projects’ efforts. The adoption rate of these forages among farmers has been found to be rather low, with the NDDP reporting only 1.9 % of farms surveyed and an ICRAF report ind...


Sinja, J.Nyangaga, J.Karugia, Joseph T.Waithaka, M.M.Mwangi, D.M.Romney, D.L.[Factors influencing farmer-to-farmer extension of forage legume technology]Factors influencing farmer-to-farmer extension of forage legume technology

Immunity against the bovine intracellular protozoan parasite Theileria parva has been shown to be mediated through the destruction of parasite infected lymphocytes by MHC class I restricted CD8+ CTL. Six parasite proteins targeted by CTL from T. parva immune cattle have been identified and raised...


Graham, S.P.Pelle, RogerVilliers, Etienne P. deYamage, M.Mwangi, D.M.Honda, Y.Ellis, S.A.MacHugh, Niall D.Morrison, W. IvanTaracha, E.L.N.[Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva]Identification of bovine cytotoxic T lymphocyte epitopes on the intracellular parasite Theileria Parva

Theileria parva antigens recognized by cytotoxic T lymphocytes (CTLs) are prime vaccine candidates against East Coast Fever in cattle. A strategy for enhancing induction of parasite-specific T cell responses by increasing recruitment and activation of dendritic cells (DCs) at the immunization sit...


Mwangi, D.M.Honda, Y.Graham, S.P.Pelle, RogerTaracha, E.L.N.Gachanja, J.Nyanjui, J.K.Bray, J.Palmer, G.H.Brown, W.C.Mwangi, W.[Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses]Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses

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