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Journal Article 2016-09-02

Autor: Olds, Cassandra L. Mwaura, S. Odongo, David O. Scoles, Glen A. Bishop, R. Daubenberger, C.A.

Background Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine targeting tick proteins that are involved in attachment and feeding might affect...

Enlace original: https://cgspace.cgiar.org/handle/10568/80663

Investigación en Agricultura
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Olds, Cassandra L. ,  Mwaura, S. ,  Odongo, David O. ,  Scoles, Glen A. ,  Bishop, R. ,  Daubenberger, C.A. ,  [Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission] ,  Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission
Journal Article 2002-03-15

Autor: Skilton, Robert A. Bishop, Richard P. Katende, J.M. Mwaura, S. Morzaria, S.P.

An improved Theileria parva DNA detection assay based on the polymerase chain reaction (PCR) using primers derived from the 104 kDa antigen (p104) gene was developed to detect parasite DNA in blood spots on filter paper. The specificity of the assay was validated using DNA from a wide range of ca...

Enlace original: https://cgspace.cgiar.org/handle/10568/21168

Investigación en Agricultura
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Skilton, Robert A. ,  Bishop, Richard P. ,  Katende, J.M. ,  Mwaura, S. ,  Morzaria, S.P. ,  [The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay] ,  The persistence of Theileria parva infection in cattle immunised using two stocks which differ in their ability to induce a carrier state: Analysis using a novel blood spot PCR assay
Journal Article 2005

Autor: Musoke, A.J. Rowlands, G.J. Nene, Vishvanath Nyanjui, J. Katende, J. Spooner, P.R. Mwaura, S. Odongo, D. Nkonge, C. Mbogo, S. Bishop, Richard P. Morzaria, S.P.

Two recombinant vaccines against Theileria parva, based on a near full-length version of the sporozoite surface antigen p67 (p67635), or an 80 amino acid C-terminal section (p67C), were evaluated by exposure of immunized cattle to natural tick challenge in two sites at the Kenya Coast and one i...

Enlace original: https://cgspace.cgiar.org/handle/10568/33216

Investigación en Agricultura
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Musoke, A.J. ,  Rowlands, G.J. ,  Nene, Vishvanath ,  Nyanjui, J. ,  Katende, J. ,  Spooner, P.R. ,  Mwaura, S. ,  Odongo, D. ,  Nkonge, C. ,  Mbogo, S. ,  Bishop, Richard P. ,  Morzaria, S.P. ,  [Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge] ,  Subunit vaccine based on the p67 major surface protein of Theileria parva sporozoites reduces severity of infection derived from field tick challenge
Conference Paper 1999

Autor: Morzaria, S.P. Spooner, P.R. Bishop, Richard P. Mwaura, S.

The preparation of Theileria parva stabilates has been described by Cunningham et al (1973). The method is detailed in the FAO report (1978) and the FAO tick and tick-borne Disease Manual (1984). Theileria parva stabilates are a source of viable sporozoites that can be used to immunise cattle by ...

Enlace original: https://cgspace.cgiar.org/handle/10568/2866

Investigación en Agricultura
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Morzaria, S.P. ,  Spooner, P.R. ,  Bishop, Richard P. ,  Mwaura, S. ,  [The preparation of a composite stabilate for immunisation against East Coast fever] ,  The preparation of a composite stabilate for immunisation against East Coast fever
Journal Article 2016-02-15

Autor: Kanduma, E.G. Mwacharo, Joram M. Mwaura, S. Njuguna, J.N. Nzuki, I. Kinyanjui, P.W. Githaka, Naftaly W. Heyne, H. Hanotte, Olivier H. Skilton, Robert A. Bishop, Richard P.

Rhipicephalus appendiculatus is an important tick vector of several pathogens and parasitizes domestic and wild animals across eastern and southern Africa. However, its inherent genetic variation and population structure is poorly understood. To investigate whether mammalian host species, geograp...

Enlace original: https://cgspace.cgiar.org/handle/10568/69234

Investigación en Agricultura
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Kanduma, E.G. ,  Mwacharo, Joram M. ,  Mwaura, S. ,  Njuguna, J.N. ,  Nzuki, I. ,  Kinyanjui, P.W. ,  Githaka, Naftaly W. ,  Heyne, H. ,  Hanotte, Olivier H. ,  Skilton, Robert A. ,  Bishop, Richard P. ,  [Multi-locus genotyping reveals absence of genetic structure in field populations of the brown ear tick (Rhipicephalus appendiculatus) in Kenya] ,  Multi-locus genotyping reveals absence of genetic structure in field populations of the brown ear tick (Rhipicephalus appendiculatus) in Kenya
Journal Article 2012-06-15

Autor: Olds, Cassandra L. Mwaura, S. Crowder, D. Odongo, D. Oers, M.M. van Owen, J. Bishop, Richard P. Daubenberger, C.A.

Commercial vaccines based on the tick gut protein Bm86 have been successful in controlling the one-host tick Rhipicephalus (Boophilus) microplus and provide heterologous protection against certain other non-target ixodid tick species. This cross protection, however, does not extend to the three-h...

Enlace original: https://cgspace.cgiar.org/handle/10568/21033

Investigación en Agricultura
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Olds, Cassandra L. ,  Mwaura, S. ,  Crowder, D. ,  Odongo, D. ,  Oers, M.M. van ,  Owen, J. ,  Bishop, Richard P. ,  Daubenberger, C.A. ,  [Immunization of cattle with Ra86 impedes Rhipicephalus appendiculatus nymphal-to-adult molting] ,  Immunization of cattle with Ra86 impedes Rhipicephalus appendiculatus nymphal-to-adult molting

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