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A live, attenuated vaccine is currently the only viable option to control of CBPP in Africa. It has been suggested that simple modifications to current vaccines and protocols might improve efficacy in the field. In this report we compared the current vaccine formulation with a buffered preparatio...


Nkando, I.Ndinda, J.Kuria, J.Naessens, JanMbithi, F.Schnier, C.Gicheru, M.McKeever, Declan J.Wesonga, H.O.[Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle]Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle
Aye, RachealWeldearegay, Yenehiwot BerhanuLutta, H.O.Chuma, FrancisPich, A.Jores, JoergMeens, J.Naessens, Jan[Identification of targets of monoclonal antibodies that inhibit adhesion and growth in Mycoplasma mycoides subspecies mycoides]Identification of targets of monoclonal antibodies that inhibit adhesion and growth in Mycoplasma mycoides subspecies mycoides

Techniques for in vivo depletion of lymphocytes using monoclonal antibodies have been well documented for murine systems. This model has played an important role in analysing the involvement of various lymphocyte subsets in several immune mechanisms. In mice 600 ug of Ab are generally injected in...


Scheerlinck, J.P.Naessens, Jan[In vivo depletion of T-cell subsets in cattle]In vivo depletion of T-cell subsets in cattle

The membrane-associated enzyme l-α-glycerol-3-phosphate oxidase (GlpO) of Mycoplasma mycoides subs. mycoides (Mmm), the causal agent of contagious bovine pleuropneumonia (CBPP) has been identified as a virulence factor responsible for the release of toxic by-products such as H2O2 that mediate hos...


Mulongo, M.M.Frey, J.Smith, K.Schnier, C.Wesonga, H.O.Naessens, JanMcKeever, Declan J.[Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides in cattle fail to generate neutralizing antibodies and succumb to disease on challenge]Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides in cattle fail to generate neutralizing antibodies and succumb to disease on challenge

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