Descubre y comparte nuestro conocimiento público

Se han encontrado 110 recursos

Resultados de búsqueda

Contagious bovine pleuropneumonia (CBPP), caused by Mycoplasma mycoides subsp. mycoides, is an important livestock disease in Africa. The current control measures rely on a vaccine with limited efficacy and occasional severe side effects. Knowledge of the protective arms of immunity involved in t...


Sacchini, F.Naessens, JanAwino, EliasHeller, M.Hlinak, A.Haider, W.Sterner-Kock, AnjaJores, Joerg[A minor role of CD4+ T lymphocytes in the control of a primary infection of cattle with Mycoplasma mycoides subsp. Mycoides]A minor role of CD4+ T lymphocytes in the control of a primary infection of cattle with Mycoplasma mycoides subsp. Mycoides

East coast fever (ECF) is a major tick-borne disease caused by the apicomplexan parasite Theileria parva (1). ECF is an acute leukemia-like disease of cattle that is endemic in eastern, central and souther Africa, where it is responsible for significant mortality and losses in animal production. ...


Grab, D.J.Naessens, JanOle-MoiYoi, O.K.[Evidence for ADP-ribosylation and G protein in Theileria parva-transformed bovine lymphocytes]Evidence for ADP-ribosylation and G protein in Theileria parva-transformed bovine lymphocytes

The membrane-associated form of the variable surface glycoprotein (mfVSG) from African trypanosomes is a potent macrophage activator capable of inducing production of tumor necrosis factor z (TNFalfa) in both bovine and murine models. Using a bovine model. we have re-investigated the hypothesis t...


Sileghem, M.R.Saya, R.Grab, D.J.Naessens, Jan[An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes]An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes

Serum Ig from Trypanosoma congolense-infected cattle were affinity-purified using immobilised trypanosome or non-trypanosome antigens (beta-galactosidase, cytochrome C and ferritin). The bound and unbound IgG and IgM fractions were collected and tested in ELISA for reactivity to each antigen. The...


Buza, J.Naessens, Jan[Trypanosome non-specific IgM antibodies detected in serum of Trypanosoma congolense-infected cattle are polyreactive]Trypanosome non-specific IgM antibodies detected in serum of Trypanosoma congolense-infected cattle are polyreactive

Gene-knockout mice have been extensively used in the study of several malaria-induced pathologies. Some investigators believe that the deficient, infected mice mimic disease aspects produced in the absence of the target gene, but others believe that the deficient mice models mainly explain the ef...


Hernández Valladares, M.Naessens, JanIraqi, F.A.[Gene-knockout mice in malaria research: Useful or misleading?]Gene-knockout mice in malaria research: Useful or misleading?

Murine models have proved to be excellent tools in the support of studies of the human genetic bases of malaria resistance and have enabled the mapping of 12 resistance loci, eight of them controlling parasitic levels and four controlling cerebral malaria. Further studies using this method have i...


Hernández Valladares, M.Naessens, JanIraqi, F.A.[Genetic resistance to malaria in mouse models]Genetic resistance to malaria in mouse models
Autor: Naessens, Jan

Although specific immunoglobulin (Ig) and B cell responses are suppressed during an infection, there is a general activation of the humoral component of the immune system in infections with African trypanosomes. The changes in the humoral immune systems during infections are summarised in this pa...


Naessens, Jan[CD5+ B lymphocytes in cattle infected with African trypanosomiasis]CD5+ B lymphocytes in cattle infected with African trypanosomiasis
Bensaid, A.M.Naessens, JanKemp, Stephen J.Black, S.J.Shapiro, S.Z.Teale, A.J.[An immunochemical analysis of class I (BoLA) molecules on the surface of bovine cells]An immunochemical analysis of class I (BoLA) molecules on the surface of bovine cells
Taylor, K.A.Gichuki, B.Lutje, V.Naessens, JanWilliams, D.J.L.[In vitro activation and detection of antibody-secreting cells from Trypanosoma congolense-infected cattle]In vitro activation and detection of antibody-secreting cells from Trypanosoma congolense-infected cattle
Goddeeris, B.M.Morrison, W. IvanNaessens, JanMagondu, J.G.[The bovine autologous mixed leukocyte reaction. A proliferative response of non-T cells under the control of monocytes]The bovine autologous mixed leukocyte reaction. A proliferative response of non-T cells under the control of monocytes

Selecciona los documentos para visualizarlos

Nombre del archivo Ver recurso