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Martini, J.C. deMacHugh, Niall D.Naessens, JanTeale, A.J.[Differential in vitro and in vivo expression of MHC class II antigens in bovine lymphocytes infected by Theileria parva]Differential in vitro and in vivo expression of MHC class II antigens in bovine lymphocytes infected by Theileria parva

Alpha gamma T cells in ruminants can be subdivided in two or more subpopulations on the basis of the expression of surface antigen WC1, which can exist in different isoforms. In this study, 18 monoclonal antibodies (mAbs) submitted to the Third International Workshop that were predicted to react ...


Davis, W.C.Brown, W.C.Hamilton, M.J.Wyatt, C.R.Orden, J.A.Khalid, A.M.Naessens, Jan[Analysis of monoclonal antibodies specific for the gamma alpha TcR]Analysis of monoclonal antibodies specific for the gamma alpha TcR
Williams, D.J.L.Taylor, K.A.Newson, J.Naessens, Jan[Specificity of serum antibodies derived from Trypanosoma congolense infected cattle]Specificity of serum antibodies derived from Trypanosoma congolense infected cattle

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...


Hernández Valladares, M.Naessens, JanGibson, John P.Musoke, A.J.Nagda, S.M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Confirmation and dissection of QTL controlling resistance to malaria in mice]Confirmation and dissection of QTL controlling resistance to malaria in mice

Mice infected with African trypanosomes produce exceptionally large amounts of serum IgM, a major part of which binds to non-trypanosome antigens such as trinitrophenol and single-strand DNA. In this paper, we describe that in cattle infected with Trypanosoma congolense and T. vivax, similar anti...


Buza, J.J.Sileghem, M.R.Gwakisa, P.S.Naessens, Jan[CD5+B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense infected cattle]CD5+B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense infected cattle
Flynn, J.N.McKeever, Declan J.Sileghem, M.R.Naessens, Jan[Modulation of the phenotype and function of bovine afferent lymph cells during infection with Trypanosoma congolense]Modulation of the phenotype and function of bovine afferent lymph cells during infection with Trypanosoma congolense
Baldwin, C.L.MacHugh, Niall D.Ellis, J.A.Naessens, JanNewson, J.Morrison, W. Ivan[Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: Tissue distribution and functional characteristics of the target antigens]Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: Tissue distribution and functional characteristics of the target antigens
Baldwin, C.L.Teale, A.J.Naessens, JanGoddeeris, B.M.MacHugh, Niall D.Morrison, W. Ivan[Characterization of a subset of bovine T lymphocytes that express BoT4 by monoclonal antibodies and function: Similarity to lymphocytes defined by human T4 and murine L3T4]Characterization of a subset of bovine T lymphocytes that express BoT4 by monoclonal antibodies and function: Similarity to lymphocytes defined by human T4 and murine L3T4

Monoclonal antibodies potentially specific for antigens expressed or upregulated on activated leukocytes were selected for further analysis from the panel submitted to the third international workshop on ruminant leukocyte antigens. The kinetics of expression of these activation antigens or resti...


Davis, W.C.Naessens, JanBrown, W.C.Ellis, J.A.Hamilton, M.J.Canton, G.H.Barbosa, J.J.R.Ferens, W.Bohach, G.A.[Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes]Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes

Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a devastating respiratory disease mainly affecting cattle in sub-Saharan Africa. The current vaccines are based on live-attenuated Mmmstrains and present problems with temperature stabili...


Nkando, I.Pérez Casal, J.Mwirigi, M.Prysliak, T.Townsend, H.Berberov, E.Kuria, J.Mugambi, J.Soi, R.Liljander, Anne M.Jores, JoergGerdts, V.Potter, A.Naessens, JanWesonga, H.O.[Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia]Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia

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