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Journal Article 2011-09-29

Autor: Nkando, I. Ndinda, J. Kuria, J. Naessens, Jan Mbithi, F. Schnier, C. Gicheru, M. McKeever, Declan J. Wesonga, H.O.

A live, attenuated vaccine is currently the only viable option to control of CBPP in Africa. It has been suggested that simple modifications to current vaccines and protocols might improve efficacy in the field. In this report we compared the current vaccine formulation with a buffered preparatio...

Enlace original: https://cgspace.cgiar.org/handle/10568/16450

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Nkando, I. ,  Ndinda, J. ,  Kuria, J. ,  Naessens, Jan ,  Mbithi, F. ,  Schnier, C. ,  Gicheru, M. ,  McKeever, Declan J. ,  Wesonga, H.O. ,  [Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle] ,  Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle
Journal Article 2016-10-01

Autor: Mwirigi, M. Nkando, I. Olum, M. Attah-Poku, S. Ochanda, H. Berberov, E. Potter, A. Gerdts, V. Pérez Casal, J. Wesonga, H.O. Soi, R. Naessens, Jan

Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease caused byMycoplasma mycoides subsp. mycoides (Mmm) which is widespread in Africa. The capsule polysaccharide (CPS) of Mmm is one of the few identified virulence determinants. In a previous study, immunization of mice against...

Enlace original: https://cgspace.cgiar.org/handle/10568/76131

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Mwirigi, M. ,  Nkando, I. ,  Olum, M. ,  Attah-Poku, S. ,  Ochanda, H. ,  Berberov, E. ,  Potter, A. ,  Gerdts, V. ,  Pérez Casal, J. ,  Wesonga, H.O. ,  Soi, R. ,  Naessens, Jan ,  [Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia] ,  Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia
Journal Article 2005-01-28

Autor: Naessens, Jan Kitani, H. Nakamura, Y. Yagi, Y. Sekikawa, K. Iraqi, F.A.

Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-α (TNF-α), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia develop...

Enlace original: https://cgspace.cgiar.org/handle/10568/1434

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Naessens, Jan ,  Kitani, H. ,  Nakamura, Y. ,  Yagi, Y. ,  Sekikawa, K. ,  Iraqi, F.A. ,  [TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection] ,  TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Journal Article 2004-11-30

Autor: Naessens, Jan Kitani, H. Momotani, E. Sekikawa, K. Nthale, J.M. Iraqi, F.A.

C57BL/6 mice deficient in one or two copies of the gene for tumor necrosis factor alpha (TNF-α) were more susceptible to Trypanosoma congolense infection than their resistant, wild-type counterparts. The number of TNF-α genes was correlated with the capacity to control parasitaemia and with survi...

Enlace original: https://cgspace.cgiar.org/handle/10568/1397

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Naessens, Jan ,  Kitani, H. ,  Momotani, E. ,  Sekikawa, K. ,  Nthale, J.M. ,  Iraqi, F.A. ,  [Susceptibility of TNF-α-deficient mice to Trypanosoma congolense is not due to a defective antibody response] ,  Susceptibility of TNF-α-deficient mice to Trypanosoma congolense is not due to a defective antibody response
Journal Article 1991

Autor: Naessens, Jan
Enlace original: https://cgspace.cgiar.org/handle/10568/29844

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Naessens, Jan ,  [Characterisation of lymphocyte populations in African buffalo (Syncerus caffer) and water buck (Kobus defassa) with workshop monoclonal antibodies] ,  Characterisation of lymphocyte populations in African buffalo (Syncerus caffer) and water buck (Kobus defassa) with workshop monoclonal antibodies
Journal Article 1991

Autor: Fritsch, G. Nelson, R.T. Muiya, P. Naessens, Jan Black, S.J.
Enlace original: https://cgspace.cgiar.org/handle/10568/29846

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Fritsch, G. ,  Nelson, R.T. ,  Muiya, P. ,  Naessens, Jan ,  Black, S.J. ,  [Characterization of bovine haemopoietic progenitor cells using monoclonal antibodies and fluorocytometry] ,  Characterization of bovine haemopoietic progenitor cells using monoclonal antibodies and fluorocytometry
Journal Article 1995

Autor: Sileghem, M.R. Naessens, Jan

Murine models have suggested that CD8 T cells might play a major parasite-promoting role in African trypanosomiasis. To assess the role of these cells in a natural host environment, we have depleted CD8 cells from Boran cattle in vivo and subsequently infected these animals with Trypanosoma congo...

Enlace original: https://cgspace.cgiar.org/handle/10568/35336

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Sileghem, M.R. ,  Naessens, Jan ,  [Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?] ,  Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?
Journal Article 2002-09-15

Autor: Naessens, Jan Teale, A.J. Sileghem, M.R.

Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differenc...

Enlace original: https://cgspace.cgiar.org/handle/10568/1537

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Naessens, Jan ,  Teale, A.J. ,  Sileghem, M.R. ,  [Identification of mechanisms of natural resistance to African trypanosomiasis in cattle] ,  Identification of mechanisms of natural resistance to African trypanosomiasis in cattle
Journal Article 2006-12-15

Autor: Hernández Valladares, M. Naessens, Jan Musoke, A.J. Sekikawa, K. Rihet, P. Ole-MoiYoi, O.K. Busher, P. Iraqi, F.A.

Tumor necrosis factor alpha (Tnf) plays a pleiotropic role in murine malaria. Some investigations have correlated Tnf with hypothermia, hyperlactatemia, hypoglycemia, and a suppression of the erythropoietic response, although others have not. In this study, we have evaluated parasitemia, survival...

Enlace original: https://cgspace.cgiar.org/handle/10568/1400

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Hernández Valladares, M. ,  Naessens, Jan ,  Musoke, A.J. ,  Sekikawa, K. ,  Rihet, P. ,  Ole-MoiYoi, O.K. ,  Busher, P. ,  Iraqi, F.A. ,  [Pathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ] ,  Pathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ
Journal Article 1988

Autor: Bensaid, A.M. Naessens, Jan Kemp, Stephen J. Black, S.J. Shapiro, S.Z. Teale, A.J.
Enlace original: https://cgspace.cgiar.org/handle/10568/28700

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Bensaid, A.M. ,  Naessens, Jan ,  Kemp, Stephen J. ,  Black, S.J. ,  Shapiro, S.Z. ,  Teale, A.J. ,  [An immunochemical analysis of class I (BoLA) molecules on the surface of bovine cells] ,  An immunochemical analysis of class I (BoLA) molecules on the surface of bovine cells

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