Descubre y comparte nuestro conocimiento público

Se han encontrado 11 recursos

Resultados de búsqueda

Journal Article 2003

Autor: Naessens, Jan Leak, S.G.A. Kennedy, D.J. Kemp, Stephen J. Teale, A.J.

West African N'Dama cattle have developed a genetic capacity to survive, reproduce and remain productive under trypanosomosis risk. The cellular and molecular bases of this so-called trypanotolerance are not known, but the trait is manifested by the N'Dama's greater capacity to control parasitae...

Enlace original: https://cgspace.cgiar.org/handle/10568/33227

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Leak, S.G.A. ,  Kennedy, D.J. ,  Kemp, Stephen J. ,  Teale, A.J. ,  [Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense] ,  Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense
Journal Article 2004

Autor: Naessens, Jan Kitani, H. Momotani, E. Sekikawa, K. Nthale, J.M. Iraqi, F.A.

C57BL/6 mice deficient in one or two copies of the gene for tumor necrosis factor alpha (TNF-alpha) were more susceptible to Trypanosoma congolense infection than their resistant, wild-type counterparts. The number of TNF-alpha genes was correlated with the capacity to control parasitaemia and ...

Enlace original: https://cgspace.cgiar.org/handle/10568/29973

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Kitani, H. ,  Momotani, E. ,  Sekikawa, K. ,  Nthale, J.M. ,  Iraqi, F.A. ,  [Susceptibility of TNF-alpha-deficient mice to Trypanosoma congolense is not due to a defective antibody response] ,  Susceptibility of TNF-alpha-deficient mice to Trypanosoma congolense is not due to a defective antibody response
Journal Article 2002

Autor: Naessens, Jan Teale, A.J. Sileghem, M.R.

Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differen...

Enlace original: https://cgspace.cgiar.org/handle/10568/33225

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Teale, A.J. ,  Sileghem, M.R. ,  [Identification of mechanisms of natural resistance to African trypanosomiasis in cattle] ,  Identification of mechanisms of natural resistance to African trypanosomiasis in cattle
Newsletter 2001

Autor: Naessens, Jan Leak, S.G.A. Kennedy, D.J. Kemp, Stephen J. Teale, A.J.

West African N'Dama cattle have developed a genetic capacity to survive, reproduce and remain productive under trypanosomosis risk. The cellular and molecular bases of this so-called trypanotolerance are not known, but the trait is manifested by the N'Dama's greater capacity to control parasitaem...

Enlace original: https://cgspace.cgiar.org/handle/10568/28679

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Leak, S.G.A. ,  Kennedy, D.J. ,  Kemp, Stephen J. ,  Teale, A.J. ,  [Responses of bovine chimaeras combining trypanosomiasis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense] ,  Responses of bovine chimaeras combining trypanosomiasis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense
Journal Article 2007

Autor: Hernández Valladares, M. Naessens, Jan Iraqi, F.A.

Gene-knockout mice have been extensively used in the study of several malaria-induced pathologies. Some investigators believe that the deficient, infected mice mimic disease aspects produced in the absence of the target gene, but others believe that the deficient mice models mainly explain the ef...

Enlace original: https://cgspace.cgiar.org/handle/10568/33188

Investigación en Agricultura
Enlace permanente
Hernández Valladares, M. ,  Naessens, Jan ,  Iraqi, F.A. ,  [Gene-knockout mice in malaria research: Useful or misleading?] ,  Gene-knockout mice in malaria research: Useful or misleading?
Journal Article 2005

Autor: Hernández Valladares, M. Naessens, Jan Iraqi, F.A.

Murine models have proved to be excellent tools in the support of studies of the human genetic bases of malaria resistance and have enabled the mapping of 12 resistance loci, eight of them controlling parasitic levels and four controlling cerebral malaria. Further studies using this method have i...

Enlace original: https://cgspace.cgiar.org/handle/10568/33187

Investigación en Agricultura
Enlace permanente
Hernández Valladares, M. ,  Naessens, Jan ,  Iraqi, F.A. ,  [Genetic resistance to malaria in mouse models] ,  Genetic resistance to malaria in mouse models
Journal Article 1996

Autor: Williams, D.J.L. Taylor, K. Newson, J. Gichuki, B. Naessens, Jan

It has been reported that some breeds of cattle such as the N'Dama mount a more effective antibody response to the variable surface glycoprotein coat of trypanosomes and that this may contribute to their ability to control the infection. Thus we have investigated antibody responses to surface exp...

Enlace original: https://cgspace.cgiar.org/handle/10568/29382

Investigación en Agricultura
Enlace permanente
Williams, D.J.L. ,  Taylor, K. ,  Newson, J. ,  Gichuki, B. ,  Naessens, Jan ,  [The role of anti-variable surface glycoprotein antibody responses in bovine trypanotolerance] ,  The role of anti-variable surface glycoprotein antibody responses in bovine trypanotolerance
Journal Article 1998

Autor: Syfrig, J. Wells, C. Daubenberger, C.A. Musoke, A.J. Naessens, Jan

A flow cytometric method using anti-parasite antibodies was developed to measure binding of theileria parva sporozoites to the target bovine lymphocyte membrane. Parasite-host cell interactions could be inhibited by monoclonal antibodies to bovine MHC class I and partially by one of two antibodie...

Enlace original: https://cgspace.cgiar.org/handle/10568/28537

Investigación en Agricultura
Enlace permanente
Syfrig, J. ,  Wells, C. ,  Daubenberger, C.A. ,  Musoke, A.J. ,  Naessens, Jan ,  [Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites] ,  Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites
Conference Paper 2001

Autor: Iraqi, F.A. Hernández Valladares, M. Ogugo, M. Njoroge, T. Nthale, J. King, R. Naessens, Jan Gibson, P.J. Musoke, A.J. Ole-MoiYoi, O.K.
Enlace original: https://cgspace.cgiar.org/handle/10568/50553

Investigación en Agricultura
Enlace permanente
Iraqi, F.A. ,  Hernández Valladares, M. ,  Ogugo, M. ,  Njoroge, T. ,  Nthale, J. ,  King, R. ,  Naessens, Jan ,  Gibson, P.J. ,  Musoke, A.J. ,  Ole-MoiYoi, O.K. ,  [Fine mapping of quantitative trait loci resistance to malaria using advanced intercross lines of mice] ,  Fine mapping of quantitative trait loci resistance to malaria using advanced intercross lines of mice

Selecciona los documentos para visualizarlos

Nombre del archivo Ver recurso
Marcar todos
Limpiar todo