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Baldwin, C.L.Teale, A.J.Naessens, JanGoddeeris, B.M.MacHugh, Niall D.Morrison, W. Ivan[Characterization of a subset of bovine T lymphocytes that express BoT4 by monoclonal antibodies and function: Similarity to lymphocytes defined by human T4 and murine L3T4]Characterization of a subset of bovine T lymphocytes that express BoT4 by monoclonal antibodies and function: Similarity to lymphocytes defined by human T4 and murine L3T4

Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a devastating respiratory disease mainly affecting cattle in sub-Saharan Africa. The current vaccines are based on live-attenuated Mmmstrains and present problems with temperature stabili...


Nkando, I.Pérez Casal, J.Mwirigi, M.Prysliak, T.Townsend, H.Berberov, E.Kuria, J.Mugambi, J.Soi, R.Liljander, Anne M.Jores, JoergGerdts, V.Potter, A.Naessens, JanWesonga, H.O.[Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia]Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia

Members of ‘Mycoplasma mycoides cluster’ are important ruminant pathogens in Africa. Diseases caused by these Mycoplasma negatively affect the agricultural sector especially in developing countries through losses in livestock productivity, mortality and international trade restrictions. There is ...


Kama-Kama, F.Midiwo, JacobNg'ang'a, J.Maina, N.Schieck, Elise G.Omosa, L.K.Osanjo, G.Naessens, Jan[Selected Ethno-medicinal plants from Kenya with in vitroactivity against major African livestock pathogens belonging to the “Mycoplasma mycoides cluster’]Selected Ethno-medicinal plants from Kenya with in vitroactivity against major African livestock pathogens belonging to the “Mycoplasma mycoides cluster’
Naessens, JanOlubayo, R.O.Davis, W.C.Hopkins, J.[Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants]Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants

Infections caused by Mycoplasma species belonging to the ‘mycoides cluster’ negatively affect the agricultural sector through losses in livestock productivity. These Mycoplasma strains are resistant to many conventional antibiotics due to the total lack of cell wall. Therefore, there is an urgent...


Kama-Kama, F.Omosa, L.K.Ng'ang'a, J.Maina, N.Osanjo, G.Yaouba, SouaibouIlias, M.Midiwo, JacobNaessens, Jan[Antimycoplasmal Activities of Compounds from Solanum aculeastrum and Piliostigma thonningii against Strains from the Mycoplasma mycoides Cluster]Antimycoplasmal Activities of Compounds from Solanum aculeastrum and Piliostigma thonningii against Strains from the Mycoplasma mycoides Cluster

Techniques for in vivo depletion of lymphocytes using monoclonal antibodies have been well documented for murine systems. This model has played an important role in analysing the involvement of various lymphocyte subsets in several immune mechanisms. In mice 600 ug of Ab are generally injected in...


Scheerlinck, J.P.Naessens, Jan[In vivo depletion of T-cell subsets in cattle]In vivo depletion of T-cell subsets in cattle

The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...


Williams, D.J.L.Taylor, K.Newson, J.Naessens, JanAuthié, E.[Protective and inappropriate antibody responses in trypanosome-infected cattle]Protective and inappropriate antibody responses in trypanosome-infected cattle

Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have identified the N terminus of the transmemb...


Mulongo, M.Frey, J.Smith, K.Schnier, C.Wesonga, H.O.Naessens, JanMcKeever, Declan J.[Vaccination of cattle with the N terminus of LppQ of Mycoplasma mycoides subsp. mycoides results in type III immune complex disease upon experimental infection]Vaccination of cattle with the N terminus of LppQ of Mycoplasma mycoides subsp. mycoides results in type III immune complex disease upon experimental infection
Naessens, JanHoward, C.J.[Monoclonal antibodies reacting with bovine B cells (BoWC3, BoWC4 and BoWC5)]Monoclonal antibodies reacting with bovine B cells (BoWC3, BoWC4 and BoWC5)

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