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The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...


Naessens, JanMwangi, D.M.Buza, J.Moloo, S.K.[Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes]Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes

African buffalo (Syncerus caffer) and trypanotolerant N'Dama cattle were compared for their resistance to overcome Trypanosoma congolense and T. vivax infections. Several compartments from the immune system were followed during the infections and compared between the two species. Several parmaete...


Olubayo, R.O.Moloo, S.K.Naessens, Jan[Comparative parasite development in African buffalo and N'Dama cattle infected with either Trypanosoma congolense or T. vivax]Comparative parasite development in African buffalo and N'Dama cattle infected with either Trypanosoma congolense or T. vivax

The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...


Williams, D.J.L.Taylor, K.Newson, J.Naessens, JanAuthié, E.[Protective and inappropriate antibody responses in trypanosome-infected cattle]Protective and inappropriate antibody responses in trypanosome-infected cattle

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