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Martini, J.C. deMacHugh, Niall D.Naessens, JanTeale, A.J.[Differential in vitro and in vivo expression of MHC class II antigens in bovine lymphocytes infected by Theileria parva]Differential in vitro and in vivo expression of MHC class II antigens in bovine lymphocytes infected by Theileria parva

Alpha gamma T cells in ruminants can be subdivided in two or more subpopulations on the basis of the expression of surface antigen WC1, which can exist in different isoforms. In this study, 18 monoclonal antibodies (mAbs) submitted to the Third International Workshop that were predicted to react ...


Davis, W.C.Brown, W.C.Hamilton, M.J.Wyatt, C.R.Orden, J.A.Khalid, A.M.Naessens, Jan[Analysis of monoclonal antibodies specific for the gamma alpha TcR]Analysis of monoclonal antibodies specific for the gamma alpha TcR

Mice infected with African trypanosomes produce exceptionally large amounts of serum IgM, a major part of which binds to non-trypanosome antigens such as trinitrophenol and single-strand DNA. In this paper, we describe that in cattle infected with Trypanosoma congolense and T. vivax, similar anti...


Buza, J.J.Sileghem, M.R.Gwakisa, P.S.Naessens, Jan[CD5+B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense infected cattle]CD5+B lymphocytes are the main source of antibodies reactive with non-parasite antigens in Trypanosoma congolense infected cattle
Baldwin, C.L.MacHugh, Niall D.Ellis, J.A.Naessens, JanNewson, J.Morrison, W. Ivan[Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: Tissue distribution and functional characteristics of the target antigens]Monoclonal antibodies which react with bovine T-lymphocyte antigens and induce blastogenesis: Tissue distribution and functional characteristics of the target antigens
Baldwin, C.L.Teale, A.J.Naessens, JanGoddeeris, B.M.MacHugh, Niall D.Morrison, W. Ivan[Characterization of a subset of bovine T lymphocytes that express BoT4 by monoclonal antibodies and function: Similarity to lymphocytes defined by human T4 and murine L3T4]Characterization of a subset of bovine T lymphocytes that express BoT4 by monoclonal antibodies and function: Similarity to lymphocytes defined by human T4 and murine L3T4

Monoclonal antibodies potentially specific for antigens expressed or upregulated on activated leukocytes were selected for further analysis from the panel submitted to the third international workshop on ruminant leukocyte antigens. The kinetics of expression of these activation antigens or resti...


Davis, W.C.Naessens, JanBrown, W.C.Ellis, J.A.Hamilton, M.J.Canton, G.H.Barbosa, J.J.R.Ferens, W.Bohach, G.A.[Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes]Analysis of monoclonal antibodies reactive with molecules upregulated or expressed only on activated lymphocytes

A flow cytometric method using anti-parasite antibodies was developed to measure binding of theileria parva sporozoites to the target bovine lymphocyte membrane. Parasite-host cell interactions could be inhibited by monoclonal antibodies to bovine MHC class I and partially by one of two antibodie...


Syfrig, J.Wells, C.Daubenberger, C.A.Musoke, A.J.Naessens, Jan[Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites]Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites

Techniques for in vivo depletion of lymphocytes using monoclonal antibodies have been well documented for murine systems. This model has played an important role in analysing the involvement of various lymphocyte subsets in several immune mechanisms. In mice 600 ug of Ab are generally injected in...


Scheerlinck, J.P.Naessens, Jan[In vivo depletion of T-cell subsets in cattle]In vivo depletion of T-cell subsets in cattle
Naessens, JanHoward, C.J.[Monoclonal antibodies reacting with bovine B cells (BoWC3, BoWC4 and BoWC5)]Monoclonal antibodies reacting with bovine B cells (BoWC3, BoWC4 and BoWC5)
Muiya, P.Logan-Henfrey, L.L.Naessens, Jan[Expression of antigens on haemopoietic progenitor cells in bovine bone marrow]Expression of antigens on haemopoietic progenitor cells in bovine bone marrow

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