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Nakamura, Y.Tsuchiya, Y.Naessens, JanGibson, John P.Iraqi, F.A.[Glucocorticoid responses to Trypanosoma congolense infection in susceptible and resistance mouse strains. Abstract]Glucocorticoid responses to Trypanosoma congolense infection in susceptible and resistance mouse strains. Abstract
Williams, D.J.L.Naessens, JanMoloo, S.K.Scott, J.R.[Analysis of peripheral blood leukocyte populations in N'Dama and Boran cattle following Glossina morsitans centralis-transmitted Trypanosoma congolense infection]Analysis of peripheral blood leukocyte populations in N'Dama and Boran cattle following Glossina morsitans centralis-transmitted Trypanosoma congolense infection
Alimohammadian, M.H.Anderson, S.Brass, A.Gibson, John P.Hulme, H.Iraqi, F.A.Kemp, Stephen J.Agaba, MorrisNaessens, JanNoyes, H.A.[Identification of gene networks associated with anaemia caused by Trypanosoma congolense]Identification of gene networks associated with anaemia caused by Trypanosoma congolense

The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...


Williams, D.J.L.Taylor, K.Newson, J.Naessens, JanAuthié, E.[Protective and inappropriate antibody responses in trypanosome-infected cattle]Protective and inappropriate antibody responses in trypanosome-infected cattle

The membrane-associated enzyme l-α-glycerol-3-phosphate oxidase (GlpO) of Mycoplasma mycoides subs. mycoides (Mmm), the causal agent of contagious bovine pleuropneumonia (CBPP) has been identified as a virulence factor responsible for the release of toxic by-products such as H2O2 that mediate hos...


Mulongo, M.M.Frey, J.Smith, K.Schnier, C.Wesonga, H.O.Naessens, JanMcKeever, Declan J.[Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides in cattle fail to generate neutralizing antibodies and succumb to disease on challenge]Cattle immunized against the pathogenic l-α-glycerol-3-phosphate oxidase of Mycoplasma mycoides subs. mycoides in cattle fail to generate neutralizing antibodies and succumb to disease on challenge

Current contagious bovine pleuropneumonia (CBPP) vaccines are based on live-attenuated strains of Mycoplasma mycoides subsp. mycoides (Mmm). These vaccines have shortcomings in terms of efficacy, duration of immunity and in some cases show severe side effects at the inoculation site; hence the ne...


Pérez Casal, J.Prysliak, T.Maina, T.Wang, Y.Townsend, H.Berverov, E.Nkando, I.Wesonga, H.O.Liljander, Anne M.Jores, JoergNaessens, JanGerdts, V.Potter, A.[Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia]Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia

Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have identified the N terminus of the transmemb...


Mulongo, M.Frey, J.Smith, K.Schnier, C.Wesonga, H.O.Naessens, JanMcKeever, Declan J.[Vaccination of cattle with the N terminus of LppQ of Mycoplasma mycoides subsp. mycoides results in type III immune complex disease upon experimental infection]Vaccination of cattle with the N terminus of LppQ of Mycoplasma mycoides subsp. mycoides results in type III immune complex disease upon experimental infection

Background: Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a respiratory disease of cattle, whereas the closely related Mycoplasma mycoides subsp. capri (Mmc) is a goat pathogen. Cyto-adherence is a crucial step in host colonization b...


Aye, R.Mwirigi, M.K.Frey, J.Pilo, P.Jores, JoergNaessens, Jan[Cyto-adherence of Mycoplasma mycoides subsp. mycoides to bovine lung epithelial cells]Cyto-adherence of Mycoplasma mycoides subsp. mycoides to bovine lung epithelial cells
Lutta, H.O.Mather, A.Maina, T.W.Odongo, D.Ndiwa, Nicholas N.Wesonga, H.O.Naessens, Jan[Preliminary findings of lipoprotein B in detecting cattle chronically infected with contagious bovine pleuropneumonia]Preliminary findings of lipoprotein B in detecting cattle chronically infected with contagious bovine pleuropneumonia

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