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Techniques for in vivo depletion of lymphocytes using monoclonal antibodies have been well documented for murine systems. This model has played an important role in analysing the involvement of various lymphocyte subsets in several immune mechanisms. In mice 600 ug of Ab are generally injected in...


Scheerlinck, J.P.Naessens, Jan[In vivo depletion of T-cell subsets in cattle]In vivo depletion of T-cell subsets in cattle

The trypanosome surface coat is composed almost entirely of a homogeneous array of molecules known as variable surface glycoproteins (VSG). These molecules are highly immunogenic and elicit a strong antibody response in the infected host. Antibodies against the surface-exposed epitopes of a parti...


Williams, D.J.L.Taylor, K.Newson, J.Naessens, JanAuthié, E.[Protective and inappropriate antibody responses in trypanosome-infected cattle]Protective and inappropriate antibody responses in trypanosome-infected cattle

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