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Three international workshops held over the past eight years have addressed the identification and nomenclature of leukocyte differentiation antigens in ruminants. This article explains the progress the workshops have made.


Naessens, JanHoward, C.J.Hopkins, J.[Nomenclature and characterization of leukocyte differentiation antigens in ruminants]Nomenclature and characterization of leukocyte differentiation antigens in ruminants

The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...


Naessens, JanMwangi, D.M.Buza, J.Moloo, S.K.[Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes]Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes

From a lysate of radiolabeled Theileria parva-infected bovine lymphocytes monoclonal antibody (mAb) IL-A77 immunoprecipitated a molecule of Mr 190 000 under non-reducing conditions, which was shown to be a homodimer of a Mr 90 000 protein after reduction (Naessens et al., 1996). Purification of t...


Naessens, JanDavis, W.C.[Ruminant cluster CD71]Ruminant cluster CD71

After analysis of flowcytometry data on bovine and ovine cells and immunoprecipitation studies, a cluster of seven MAbs-CAPP2 (3W-232), IL-A164 (M430), IL-A166 (3W-226), IVA30 (3W-069), IVA31 (3W-468), IVA38 (3W-349) and IVA125 (3W 528) - was shown to detect bovine and ovine CD41/Cd61 (also known...


Mateo, A.Pintado, C.O.Lastra, J.de laDusinsky, R.Simon, M.Naessens, JanLlanes, D.[Ruminant cluster CD41/CD61]Ruminant cluster CD41/CD61

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