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Journal Article 2005-01-28

Autor: Naessens, Jan Kitani, H. Nakamura, Y. Yagi, Y. Sekikawa, K. Iraqi, F.A.

Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-α (TNF-α), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia develop...

Enlace original: https://cgspace.cgiar.org/handle/10568/1434

Investigación en Agricultura
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Naessens, Jan ,  Kitani, H. ,  Nakamura, Y. ,  Yagi, Y. ,  Sekikawa, K. ,  Iraqi, F.A. ,  [TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection] ,  TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Journal Article 2005

Autor: Naessens, Jan Kitani, H. Nakamura, Y. Yagi, Y. Sekikawa, K. Iraqi, F.A.

Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-alpha (TNF-alpha), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia...

Enlace original: https://cgspace.cgiar.org/handle/10568/32870

Investigación en Agricultura
Enlace permanente
Naessens, Jan ,  Kitani, H. ,  Nakamura, Y. ,  Yagi, Y. ,  Sekikawa, K. ,  Iraqi, F.A. ,  [TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection] ,  TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Journal Article 2002-04-15

Autor: Kitani, H. Black, S.J. Nakamura, Y. Naessens, Jan Murphy, N. Yokomizo, Y. Gibson, John P. Iraqi, F.A.

Mice whose tumor necrosis factor alpha (TNF-) genes were disrupted developed higher levels of parasitemia than wild-type mice following infection with Trypanosoma congolense IL1180 or T. brucei brucei GUTat3.1, confirming the results of earlier studies. To determine whether TNF- directly affects ...

Enlace original: https://cgspace.cgiar.org/handle/10568/1540

Investigación en Agricultura
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Kitani, H. ,  Black, S.J. ,  Nakamura, Y. ,  Naessens, Jan ,  Murphy, N. ,  Yokomizo, Y. ,  Gibson, John P. ,  Iraqi, F.A. ,  [Recombinant tumor necrosis factor alpha does not inhibit the growth of African trypanosomes in Axenic cultures] ,  Recombinant tumor necrosis factor alpha does not inhibit the growth of African trypanosomes in Axenic cultures
Journal Article 2003-06-15

Autor: Nakamura, Y. Naessens, Jan Takata, M. Taniguchi, T. Sekikawa, K. Gibson, John P. Iraqi, F.A.

The heat shock protein (HSP) 70.1 gene lies on mouse chromosome 17 among the candidates for Tir1, the major quantitative trait locus associated with response to Trypanosoma congolense infection. To evaluate whether the HSP70.1 gene is involved in the response, we compared the susceptibility of HS...

Enlace original: https://cgspace.cgiar.org/handle/10568/1553

Investigación en Agricultura
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Nakamura, Y. ,  Naessens, Jan ,  Takata, M. ,  Taniguchi, T. ,  Sekikawa, K. ,  Gibson, John P. ,  Iraqi, F.A. ,  [Susceptibility of heat shock protein 70.1-deficient C57BL/6 J, wild-type C57BL/6 J and A/J mice to Trypanosoma congolense infection] ,  Susceptibility of heat shock protein 70.1-deficient C57BL/6 J, wild-type C57BL/6 J and A/J mice to Trypanosoma congolense infection
Journal Article 2006-10-26

Autor: Kierstein, S. Noyes, H. Naessens, Jan Nakamura, Y. Pritchard, J. Gibson, John P. Kemp, Stephen J. Brass, A.

This study aimed to provide the foundation for an integrative approach to the identification of the mechanisms underlying the response to infection with Trypanosoma congolense, and to identify pathways that have previously been overlooked. We undertook a large-scale gene expression analysis study...

Enlace original: https://cgspace.cgiar.org/handle/10568/1410

Investigación en Agricultura
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Kierstein, S. ,  Noyes, H. ,  Naessens, Jan ,  Nakamura, Y. ,  Pritchard, J. ,  Gibson, John P. ,  Kemp, Stephen J. ,  Brass, A. ,  [Gene expression profiling in a mouse model for African trypanosomiasis] ,  Gene expression profiling in a mouse model for African trypanosomiasis
Journal Article 2009-06-15

Autor: Kitani, H. Naessens, Jan Kubo, M. Nakamura, Y. Iraqi, F.A. Gibson, John P. Yamakawa, M.

Synthetic antimicrobial 9-mer peptides (designated as peptides A and B) designed on the basis of insect defensins and their effects on the growth of African trypanosomes were examined using two isolates of Trypanosoma congolense, IL1180 and IL3338, and two isolates of Trypanosoma brucei brucei, I...

Enlace original: https://cgspace.cgiar.org/handle/10568/469

Investigación en Agricultura
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Kitani, H. ,  Naessens, Jan ,  Kubo, M. ,  Nakamura, Y. ,  Iraqi, F.A. ,  Gibson, John P. ,  Yamakawa, M. ,  [Synthetic nonamer peptides derived from insect defensin mediate the killing of African trypanosomes in axenic culture] ,  Synthetic nonamer peptides derived from insect defensin mediate the killing of African trypanosomes in axenic culture

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