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Many challenges face tick genomics. Ticks have large genomes and their estimated sizes vary from 1.04~7.1 x10(9) bp, about one third to over two times the size of the human genome. Karyotype studies have revealed a range in chromosome number and the sex determining system seems to be primarily dr...


Nene, Vishvanath[Tick genomics - coming of age]Tick genomics - coming of age

In order to discriminate different bovine Theileria species and to characterise genetic diversity in the pathogenic T. parva, a range of diagnostic and molecular tools have been developed. The diagnostic tools are based on recombinant antigens used in ELISAs and the molecular tools are based on p...


Morzaria, S.P.Bishop, Richard P.Nene, VishvanathSkilton, Robert A.Geysen, D.Mbogo, S.[Molecular tools for characterisation of Theileria parva]Molecular tools for characterisation of Theileria parva
Nene, VishvanathIams, K.P.Musoke, A.J.[Molecular characterization of a Theileria parva surface sporozoite antigen]Molecular characterization of a Theileria parva surface sporozoite antigen
Musoke, A.J.Nene, VishvanathIams, K.P.[Progress towards a recombinant vaccine against East Coast fever (Theileria parva infection in cattle)]Progress towards a recombinant vaccine against East Coast fever (Theileria parva infection in cattle)
Morzaria, S.P.Musoke, A.J.Young, J.Nene, Vishvanath[The biology of Theileria parva and its importance in the development of a novel vaccine]The biology of Theileria parva and its importance in the development of a novel vaccine

The Development of a recombinant Theileria parva vaccine is discussed under the following headings: mechanisms of protection against ECF [East Coast fever]; cloning and expression of p67; immunization and challenge of cattle; interpretation of immunization and challenge data.


Musoke, A.J.McKeever, Declan J.Morzaria, S.P.Nkonge, C.Nene, Vishvanath[A recombinant vaccine for Theileria parva]A recombinant vaccine for Theileria parva

Svitek, NicholasHansen, A.M.Steinaa, LucillaSaya, R.Awino, A.Nielsen, MortenBuus, SorenNene, Vishvanath[Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development]Immunoinformatics and MHC-Tetramers, revolutionary technologies for vaccine development
Rowlands, G.J.Musoke, A.J.Nene, VishvanathBishop, Richard P.Nagda, S.M.Morzaria, S.P.[Application of principal component analysis for classifying East Coast fever reactions in cattle challenged with Theileria parva]Application of principal component analysis for classifying East Coast fever reactions in cattle challenged with Theileria parva
Musoke, A.J.Nene, VishvanathMcKeever, Declan J.[Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites]Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites
Bishop, Richard P.Geysen, D.Skilton, Robert A.Odongo, D.Nene, VishvanathAllsopp, B.A.Mbogo, S.Spooner, P.R.Morzaria, S.P.[Genomic polymorphism, sexual recombination and molecular epidemiology of Theileria parva]Genomic polymorphism, sexual recombination and molecular epidemiology of Theileria parva

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