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Improvement of the livestock industry in many developing countries has been severely constrained by tick-borne diseases. The major protozoan pathogens responsible for these diseases in cattle are Theileria parva and B. annulata and Babesia bigemina and B. bovis. East Coast fever is of great econo...


Musoke, A.J.Morzaria, S.P.Nene, Vishvanath[Subunit vaccines for the control of Theileria parva]Subunit vaccines for the control of Theileria parva

Theileria parva, a tick-transmitted protozoan parasite related to Plasmodium spp., causes the disease East Coast fever, an acute and usually fatal lymphoproliferative disorder of cattle in Africa. Previous studies using sera from cattle that have survived infection identified a polymorphic immuno...


Toye, Philip G.Metzelaar, M.J.Wijngaard, P.L.J.Nene, VishvanathIams, K.P.Roose, J.Nyanjui, J.K.Gobright, E.I.Musoke, A.J.Clevers, H.C.[Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parva]Characterization of the gene encoding the polymorphic immunodominant molecule, a neutralizing antigen of Theileria parva
Nene, VishvanathIams, K.P.Gobright, E.I.Musoke, A.J.[Characterisation of the gene encoding a candidate vaccine antigen of Theileria parva sporozoites]Characterisation of the gene encoding a candidate vaccine antigen of Theileria parva sporozoites

Previous data showed that six out of a group of nine cattle inoculated with NS1-p67, a recombinant form of a 67-KDa Theileria parva sporozoite surface protein, were immune to East Coast fever. This bacterialy expressed antigen encoded all 709 amino acid residues of p67 fused to the C-terminal end...


Nene, VishvanathInumaru, S.McKeever, Declan J.Morzaria, S.P.Shaw, M.Musoke, A.J.[Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle]Characterization of an insect cell-derived Theileria parva sporozoite vaccine antigen and immunogenicity in cattle
Morzaria, S.P.Musoke, A.J.Young, J.Nene, Vishvanath[The biology of Theileria parva and its importance in the development of a novel vaccine]The biology of Theileria parva and its importance in the development of a novel vaccine
Rowlands, G.J.Musoke, A.J.Nene, VishvanathBishop, Richard P.Nagda, S.M.Morzaria, S.P.[Application of principal component analysis for classifying East Coast fever reactions in cattle challenged with Theileria parva]Application of principal component analysis for classifying East Coast fever reactions in cattle challenged with Theileria parva
Musoke, A.J.Nene, VishvanathMcKeever, Declan J.[Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites]Epitope specificity of bovine immune responses to the major surface antigen of Theileria parva sporozoites

Theileria parva, a protozoan parasite of cattle, causes a disease called East Coast fever. The disease is of economic importance because it causes high morbidity and mortality and limits the development of the cattle industry. This paper highlights the experiences with immunization against Theile...


Musoke, A.J.McKeever, Declan J.Morzaria, S.P.Nkonge, C.Nene, Vishvanath[Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen]Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen

Nyagwange, JamesTernette, NicolaTijhaar, EdwinPelle, RogerNene, Vishvanath[Proteomics of Theileria parva sporozoites]Proteomics of Theileria parva sporozoites

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