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Nyagwange, JamesTernette, NicolaTijhaar, EdwinPelle, RogerNene, Vishvanath[Proteomics of Theileria parva sporozoites]Proteomics of Theileria parva sporozoites

Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8+ cytotoxic T lymphocytes (CTL). Here, we report on the generation of seven recombinant bovine leukocyte antigens (BoLA) and reco...


Svitek, NicholasHansen, A.M.Steinaa, LucillaSaya, R.Awino, EliasNielsen, MortenBuus, SorenNene, Vishvanath[Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle]Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle
Orono, S.A.Gitao, G.C.Mpatswenumugabo, J.P.Chepkwony, M.Mutisya, Christine N.Okoth, Edward A.Bronsvoort, B.M.C. deRussell, G.C.Nene, VishvanathCook, Elizabeth A.J.[Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle]Field validation of clinical and laboratory diagnosis of wildebeest associated malignant catarrhal fever in cattle
Nyagwange, JamesAwino, EliasTijhaar, EdwinSvitek, NicholasPelle, RogerNene, Vishvanath[Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever]Leveraging the Medicines for Malaria Venture malaria and pathogen boxes to discover chemical inhibitors of East Coast fever

Theileria parva is a tick-transmitted intracellular protozoan parasite that causes East Coast fever, a fatal bovine lymphoproliferative disease. The molecular mechanisms that underlie host cell transformation by T. parva schizonts have been studied extensively, and it is known that the transcript...


Kyoko, H.Masakazu, H.Ryo, N.Yoshimasa, T.Jung-Yeon, K.Noboru, I.Nene, VishvanathChihiro, S.[A schizont-derived protein, TpSCOP, is involved in the activation of NF-κB in Theileria parva-infected lymphocytes]A schizont-derived protein, TpSCOP, is involved in the activation of NF-κB in Theileria parva-infected lymphocytes

The ticks Rhipicephalus appendiculatus and Rhipicephalus sanguineus are the main vectors of Theileria parva and Babesia spp. in cattle and dogs, respectively. Due to their impact in veterinary care and industry, improved methods against R. appendiculatus and R. sanguineus parasitism are under dev...


Sabadin, G.A.Parizi, L.F.Kiio, I.Xavier, M.A.Silva Matos, R. daCamargo-Mathias, M.I.Githaka, Naftaly W.Nene, VishvanathSilva Vaz, I. da[Effect of recombinant glutathione S-transferase as vaccine antigen against Rhipicephalus appendiculatus and Rhipicephalus sanguineus infestation]Effect of recombinant glutathione S-transferase as vaccine antigen against Rhipicephalus appendiculatus and Rhipicephalus sanguineus infestation

Bovine theileriosis caused by Theileria parva continues to be a major economic problem in many parts of Eastern, Southern, and Central Africa. Due to the unsustainable nature or the present control method-using toxic acaricides to kill ticks - alternative control methods are being sought. Live va...


Morzaria, S.P.Nene, VishvanathBishop, Richard P.Musoke, A.J.[Vaccines against Theileria parva]Vaccines against Theileria parva

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