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Kibe, M.K.Ole-MoiYoi, O.K.Nene, VishvanathKhan, B.Allsopp, B.A.Collins, N.E.Morzaria, S.P.Gobright, E.I.Bishop, B.P.[Evidence for two single copy units in Theileria parva ribosomal RNA genes]Evidence for two single copy units in Theileria parva ribosomal RNA genes
Iams, K.P.Young, J.R.Nene, VishvanathDesai, J.Webster, P.Ole-MoiYoi, O.K.Musoke, A.J.[Characterization of the gene encoding a 104 kilodalton microneme-rhoptry protein of Theileria parva]Characterization of the gene encoding a 104 kilodalton microneme-rhoptry protein of Theileria parva
McKeever, Declan J.Awino, EliasKairo, A.Gobright, E.I.Nene, Vishvanath[Bovine T cells specific for Trypanosoma brucei brucei variant surface glycoprotein recognize nonconserved areas of the molecule]Bovine T cells specific for Trypanosoma brucei brucei variant surface glycoprotein recognize nonconserved areas of the molecule

A stage-specific surface antigen of Theileria parva, p67, is the basis for the development of an anti-sporozoite vaccine for the control of East Coast fever (ECF) in cattle. By Pepscan analysis with a series of overlapping synthetic p67 peptides, the antigen was shown to contain five distinct lin...


Nene, VishvanathGobright, E.I.Bishop, Richard P.Morzaria, S.P.Musoke, A.J.[Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralising epitopes: Implications for a vaccine]Linear peptide specificity of bovine antibody responses to p67 of Theileria parva and sequence diversity of sporozoite-neutralising epitopes: Implications for a vaccine

The discipline of genomics is setting new paradigms in research approaches to resolving problems in human and animal health. We propose to determine the genome sequence of Theileria parva, a pathogen of cattle, using the random shotgun approach pioneered at The Institute for Genomic Research (TIG...


Nene, VishvanathBishop, Richard P.Morzaria, S.P.Gardner, M.J.Sugimoto, C.Ole-MoiYoi, O.K.Fraser, C.M.Irvin, A.[Theileria parva genomics reveals an atypical apicomplexan genome]Theileria parva genomics reveals an atypical apicomplexan genome

Immunity to Theileria parva infection in cattle is often parasite stock specific. The antigenic diversity which is expressed at the schizont stage of the parasite together with a wild reservoir of the organism in buffalo has complicated the development of effective disease control by immunization...


Nene, VishvanathMusoke, A.J.Gobright, E.I.Morzaria, S.P.[Conservation of the sporozoite p67 vaccine antigen in cattle-derived Theileria parva stocks with different cross-immunity profiles]Conservation of the sporozoite p67 vaccine antigen in cattle-derived Theileria parva stocks with different cross-immunity profiles
Buening, G.M.Barbet, B.Myler, P.Mahan, S.Nene, VishvanathMcGuire, T.C.[Characterization of a repetitive DNA probe for Babesia bigemina]Characterization of a repetitive DNA probe for Babesia bigemina

Rift Valley Fever virus (RVFV) causes recurrent outbreaks of acute life-threatening human and livestock illness in Africa and the Arabian Peninsula. No licensed vaccines are currently available for humans and those widely used in livestock have major safety concerns. A ‘One Health’ vaccine develo...


Warimwe, G.M.Gesharisha, J.Carr, B.V.Otieno, S.Otingah, K.Wright, D.Charleston, B.Okoth, Edward A.Elena, L.G.Lorenzo, G.Ayman, E.B.Alharbi, N.K.Al-Dubaib, M.A.Brun, A.Gilbert, S.C.Nene, VishvanathHill, A.V.S.[Chimpanzee adenovirus vaccine provides multispecies protection against Rift Valley fever]Chimpanzee adenovirus vaccine provides multispecies protection against Rift Valley fever

Many challenges face tick genomics. Ticks have large genomes and their estimated sizes vary from 1.04~7.1 x10(9) bp, about one third to over two times the size of the human genome. Karyotype studies have revealed a range in chromosome number and the sex determining system seems to be primarily dr...


Nene, Vishvanath[Tick genomics - coming of age]Tick genomics - coming of age

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