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Journal Article 2012-06-15

Autor: Nene, Vishvanath Svitek, Nicholas Toye, Philip G. Golde, W.T. Barlow, J. Buus, Soren Nielsen, Morten

T cell responses contribute to immunity against many intracellular infections. There is, for example, strong evidence that major histocompatibility complex (MHC) class I-restricted cytotoxic T lymphocytes (CTLs) play an essential role in mediating immunity to East Coast fever (ECF), a fatal lymph...

Enlace original: https://cgspace.cgiar.org/handle/10568/16432

Investigación en Agricultura
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Nene, Vishvanath ,  Svitek, Nicholas ,  Toye, Philip G. ,  Golde, W.T. ,  Barlow, J. ,  Buus, Soren ,  Nielsen, Morten ,  [Designing bovine T cell vaccines via reverse immunology] ,  Designing bovine T cell vaccines via reverse immunology
Journal Article 2014-04-28

Autor: Svitek, Nicholas Hansen, A.M. Steinaa, Lucilla Saya, R. Awino, Elias Nielsen, Morten Buus, Soren Nene, Vishvanath

Peptide-major histocompatibility complex (p-MHC) class I tetramer complexes have facilitated the early detection and functional characterisation of epitope specific CD8+ cytotoxic T lymphocytes (CTL). Here, we report on the generation of seven recombinant bovine leukocyte antigens (BoLA) and reco...

Enlace original: https://cgspace.cgiar.org/handle/10568/41612

Investigación en Agricultura
Enlace permanente

Svitek, Nicholas ,  Hansen, A.M. ,  Steinaa, Lucilla ,  Saya, R. ,  Awino, Elias ,  Nielsen, Morten ,  Buus, Soren ,  Nene, Vishvanath ,  [Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle] ,  Use of “one-pot, mix-and-read” peptide-MHC class I tetramers and predictive algorithms to improve detection of cytotoxic T lymphocyte responses in cattle

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