A live, attenuated vaccine is currently the only viable option to control of CBPP in Africa. It has been suggested that simple modifications to current vaccines and protocols might improve efficacy in the field. In this report we compared the current vaccine formulation with a buffered preparatio...
Nkando, I.
,
Ndinda, J.
,
Kuria, J.
,
Naessens, Jan
,
Mbithi, F.
,
Schnier, C.
,
Gicheru, M.
,
McKeever, Declan J.
,
Wesonga, H.O.
,
[Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle]
,
Efficacy of two vaccine formulations against contagious bovine pleuropneumonia (CBPP) in Kenyan indigenous cattle
Contagious Bovine Pleuropneumonia (CBPP) is a severe respiratory disease caused byMycoplasma mycoides subsp. mycoides (Mmm) which is widespread in Africa. The capsule polysaccharide (CPS) of Mmm is one of the few identified virulence determinants. In a previous study, immunization of mice against...
Mwirigi, M.
,
Nkando, I.
,
Olum, M.
,
Attah-Poku, S.
,
Ochanda, H.
,
Berberov, E.
,
Potter, A.
,
Gerdts, V.
,
Pérez Casal, J.
,
Wesonga, H.O.
,
Soi, R.
,
Naessens, Jan
,
[Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia]
,
Capsular polysaccharide from Mycoplasma mycoides subsp.mycoides shows potential for protection against Contagious Bovine Pleuropneumonia
Contagious bovine pleuropneumonia (CBPP) is a lung disease caused by the bacterial pathogen Mycoplasma mycoides ssp. mycoides small colony type (MmmSC). It has been spreading due to a number of factors including poor vaccine efficacy and poor sensitivity of current diagnostic tests. The purpose o...
Jores, Joerg
,
Nkando, I.
,
Sterner-Kock, Anja
,
Haider, W.
,
Poole, Elizabeth J.
,
Unger, H.
,
Muriuki, C.
,
Wesonga, H.O.
,
Taracha, E.L.N.
,
[Assessment of in vitro interferon-gamma responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type]
,
Assessment of in vitro interferon-gamma responses from peripheral blood mononuclear cells of cattle infected with Mycoplasma mycoides ssp. mycoides small colony type
Mycoplasma mycoides subsp. mycoides (Mmm) is the causative agent of contagious bovine pleuropneumonia (CBPP), a devastating respiratory disease mainly affecting cattle in sub-Saharan Africa. The current vaccines are based on live-attenuated Mmmstrains and present problems with temperature stabili...
Nkando, I.
,
Pérez Casal, J.
,
Mwirigi, M.
,
Prysliak, T.
,
Townsend, H.
,
Berberov, E.
,
Kuria, J.
,
Mugambi, J.
,
Soi, R.
,
Liljander, Anne M.
,
Jores, Joerg
,
Gerdts, V.
,
Potter, A.
,
Naessens, Jan
,
Wesonga, H.O.
,
[Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia]
,
Recombinant Mycoplasma mycoides proteins elicit protective immune responses against contagious bovine pleuropneumonia
Current contagious bovine pleuropneumonia (CBPP) vaccines are based on live-attenuated strains of Mycoplasma mycoides subsp. mycoides (Mmm). These vaccines have shortcomings in terms of efficacy, duration of immunity and in some cases show severe side effects at the inoculation site; hence the ne...
Pérez Casal, J.
,
Prysliak, T.
,
Maina, T.
,
Wang, Y.
,
Townsend, H.
,
Berverov, E.
,
Nkando, I.
,
Wesonga, H.O.
,
Liljander, Anne M.
,
Jores, Joerg
,
Naessens, Jan
,
Gerdts, V.
,
Potter, A.
,
[Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia]
,
Analysis of immune responses to recombinant proteins from strains of Mycoplasma mycoides subsp. mycoides, the causative agent of contagious Bovine pleuropneumonia
The current control method for contagious bovine pleuropneumonia (CBPP) in Africa is vaccination with a live, attenuated strain of Mycoplasma mycoides subsp. mycoides(Mmm). However, this method is not very efficient and often causes serious adverse reactions. Several studies have attempted to ind...
Mwirigi, M.
,
Nkando, I.
,
Aye, R.
,
Soi, R.
,
Ochanda, H.
,
Berberov, E.
,
Potter, A.
,
Gerdts, V.
,
Pérez Casal, J.
,
Naessens, Jan
,
Wesonga, H.O.
,
[Experimental evaluation of inactivated and live attenuated vaccines against Mycoplasma mycoides subsp. Mycoides]
,
Experimental evaluation of inactivated and live attenuated vaccines against Mycoplasma mycoides subsp. Mycoides