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A comparison of F2 and F6/7 inter-cross lines of mice, derived from CBA and SWR parental strains, has provided strong evidence for several previously undetected quantitative trait loci (QTL) for resistance to Heligmosomoides bakeri. Five QTL affecting average faecal egg counts and/or worm burdens...


Behnke, J.M.Menge, D.M.Nagda, S.M.Noyes, H.Iraqi, F.A.Kemp, Stephen J.Mugambi, R.J.M.Baker, R.L.Wakelin, D.Gibson, John P.[Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice]Quantitative trait loci for resistance to Heligmosomoides bakeri and associated immunological and pathological traits in mice: comparison of loci on chromosomes 5, 8 and 11 in F2 and F6/7 inter-cross lines of mice

C57BL/6J mice are relatively resistant to trypanosomosis compared to BALB/c or A/J mice. Bloodstream trypanosomes are partly dependent on the host for lipid supply and the plasma lipid levels differ between resistant and susceptible mice. Furthermore, genes controlling plasma lipid levels are dif...


Hassan, M.Agaba, MorrisBulimo, WallaceNoyes, H.Brass, A.Hinsley, T.Iraqi, F.A.Kemp, Stephen J.[Role of plasma lipids in the susceptibility of laboratory mice to trypanosomosis]Role of plasma lipids in the susceptibility of laboratory mice to trypanosomosis

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