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High-through put technologies inevitably produce vast quantities of data. This presents challenges in terms of developing effective analysis methods, particularly where the analysis involves combining data derived from different experimental technologies. In this investigation, a systematic appro...


Rennie, C.Hulme, H.Fisher, P.Halp, L.Agaba, MorrisNoyes, H.A.Kemp, Stephen J.Brass, A.[A systematic, data-driven approach to the combined analysis of microarray and QTL data]A systematic, data-driven approach to the combined analysis of microarray and QTL data

Trypanosoma congolense is a protozoan parasite that causes severe diseases in livestock. Three major quantative trait loci (QTL), Tir1, Tir2, and Tir3, control the survival time of mice after infection with T. congolense. Congenic mice carrying the C57BL/6 resistance alleles on the A/J background...


Rathkolb, B.Noyes, H.A.Brass, A.Dark, P.Fuchs, H.Gailus-Durner, V.Gibson, John P.Angelis, M.H. deOgugo, M.Iraqi, F.A.Kemp, Stephen J.Naessens, JanPope, M.E.Wolf, E.Agaba, Morris[Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection]Clinical chemistry of congenic mice with quantitative trait loci for predicted responses to Trypanosoma congolense infection

Trypanosoma congolense are extracellular protozoan parasites of the blood stream of artiodactyls and are one of the main constraints on cattle production in Africa. In cattle, anaemia is the key feature of disease and persists after parasitaemia has declined to low or undetectable levels, but tre...


Noyes, H.A.Alimohammadian, M.H.Agaba, MorrisBrass, A.Fuchs, H.Gailus-Durner, V.Hulme, H.Iraqi, F.A.Kemp, Stephen J.Rathkolb, B.Wolf, E.Angelis, M.H. deRoshandel, D.Naessens, Jan[Mechanisms controlling anaemia in Trypanosoma congolense infected mice]Mechanisms controlling anaemia in Trypanosoma congolense infected mice

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