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Background Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine targeting tick proteins that are involved in attachment and feeding might affect...


Olds, Cassandra L.Mwaura, S.Odongo, David O.Scoles, Glen A.Bishop, R.Daubenberger, C.A.[Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission]Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission

Napier grass Stunt Disease (NSD) is a severe disease of Napier grass (Pennisetum purpureum) in Eastern Africa, caused by the leafhopper-transmitted bacterium Candidatus Phytoplasma oryzae. The pathogen severely impairs the growth of Napier grass, the major fodder for dairy cattle in Eastern Afric...


Wambua, L.Schneider, B.Okwaro, A.Wanga, J.O.Imali, O.Wambua, P.N.Agutu, L.Olds, Cassandra L.Jones, Christopher S.Masiga, Daniel K.Midega, C.A.O.Khana, Z.Jores, JoergFischer, A.[Development of field-applicable tests for rapid and sensitive detection of Candidatus Phytoplasma oryzae]Development of field-applicable tests for rapid and sensitive detection of Candidatus Phytoplasma oryzae
Odongo, D.Olds, Cassandra L.Daubenberger, C.A.Musoke, A.J.Scoles, Glen A.Knowles, D.Bishop, Richard P.[Immunological control of ticks: Research towards development of an anti-tick vaccine for cattle]Immunological control of ticks: Research towards development of an anti-tick vaccine for cattle

Rothen, J.Bishop, Richard P.Mwaura, S.Pfluger, V.Daubenberger, C.A.Olds, Cassandra L.[Mapping distributions of ticks and tick-borne diseases in Africa: Effects of climate change and the implications for human and animal health]Mapping distributions of ticks and tick-borne diseases in Africa: Effects of climate change and the implications for human and animal health

The tick population of Africa includes several important genera belonging to the family Ixodidae. Many of these ticks are vectors of protozoan and rickettsial pathogens including Theileria parva that causes East Coast fever, a debilitating cattle disease endemic to eastern, central and southern A...


Rothen, J.Githaka, Naftaly W.Kanduma, E.G.Olds, Cassandra L.Pflueger, V.Mwaura, S.Bishop, Richard P.Daubenberger, C.A.[Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African Ixodid tick species]Matrix-assisted laser desorption/ionization time of flight mass spectrometry for comprehensive indexing of East African Ixodid tick species

Commercial vaccines based on the tick gut protein Bm86 have been successful in controlling the one-host tick Rhipicephalus (Boophilus) microplus and provide heterologous protection against certain other non-target ixodid tick species. This cross protection, however, does not extend to the three-h...


Olds, Cassandra L.Mwaura, S.Crowder, D.Odongo, D.Oers, M.M. vanOwen, J.Bishop, Richard P.Daubenberger, C.A.[Immunization of cattle with Ra86 impedes Rhipicephalus appendiculatus nymphal-to-adult molting]Immunization of cattle with Ra86 impedes Rhipicephalus appendiculatus nymphal-to-adult molting
Olds, Cassandra L.Mason, Kathleeen L.Scoles, Glen A.[Rhipicephalus appendiculatus ticks transmit Theileria parva from persistently infected cattle in the absence of detectable parasitemia: Implications for East Coast fever epidemiology]Rhipicephalus appendiculatus ticks transmit Theileria parva from persistently infected cattle in the absence of detectable parasitemia: Implications for East Coast fever epidemiology
Fry, Lindsay M.Knowles, Donald P.Nelson, D.Morrison, W. IvanConnelley, T.Silva, Joana C.Scoles, Glen A.Olds, Cassandra L.Brown, L.[Selection of T. parva CD4+ T-cell Candidate Antigens and T. parva Immunopathogy]Selection of T. parva CD4+ T-cell Candidate Antigens and T. parva Immunopathogy

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