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Acute Trypanosoma congolense infection induced moderate, transient anemia in N'Dama cattle (trypanotolerant) and severe anemia in Boran cattle (trypanosusceptible). Erythropoietin receptor (EpoR) was cloned and sequenced from the two breeds of cattle. A single position mutation of Tyr in the Bora...


Suliman, H.B.Logan-Henfrey, L.L.Majiwa, P.A.O.Ole-MoiYoi, O.K.Feldman, B.F.[Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense]Analysis of erythropoietin and erythropoietin receptor genes expression in cattle during acute infection with Trypanosoma congolense

A monoclonal antibody (MAb)Tv27 employed in an antigen-detection enzyme immunosorbent assay (Ag-ELISA) for diagnosis of Trypanosoma vivax infection was shown to react with a T. vivax-specific protein of an approximate molecular weight of 10 kDa. This protein is diffusely distributed throughout th...


Masake, R.A.Ole-MoiYoi, O.K.Urakawa, T.Hirumi, H.Majiwa, P.A.O.Wells, C.W.Minja, S.H.Makau, J.M.Nantulya, V.M.[Immunological characterization and expression in Escherichia coli and Baculovirus systems of a Trypanosoma vivax antigen detected in the blood of infected animals]Immunological characterization and expression in Escherichia coli and Baculovirus systems of a Trypanosoma vivax antigen detected in the blood of infected animals

The discipline of genomics is setting new paradigms in research approaches to resolving problems in human and animal health. We propose to determine the genome sequence of Theileria parva, a pathogen of cattle, using the random shotgun approach pioneered at The Institute for Genomic Research (TIG...


Nene, VishvanathBishop, Richard P.Morzaria, S.P.Gardner, M.J.Sugimoto, C.Ole-MoiYoi, O.K.Fraser, C.M.Irvin, A.[Theileria parva genomics reveals an atypical apicomplexan genome]Theileria parva genomics reveals an atypical apicomplexan genome
Goddeeris, B.M.Baldwin, C.L.Ole-MoiYoi, O.K.Morrison, W. Ivan[Improved methods for purification and depletion of monocytes from bovine peripheral blood mononuclear cells: Functional evaluation of monocytes in responses to lectins]Improved methods for purification and depletion of monocytes from bovine peripheral blood mononuclear cells: Functional evaluation of monocytes in responses to lectins

Susceptible A/J and more resistant C57BL/6J mice were infected with Plasmodium chabaudi chabaudi 54X, P.c. chabaudi AS and Plasmodium chabaudi adami 408XZ. As expected, most C57BL/6J mice survived the infections with the different isolates. But in contrast to previous observations, not all A/J ...


Hernández Valladares, M.Naessens, JanNagda, S.M.Musoke, A.J.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi]Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi
Hernández Valladares, M.Ole-MoiYoi, O.K.Iraqi, F.A.[Mapping of new quantitative trait loci (QTL) resistance to malaria in mice by a comparative mapping approach of human chromosome 5 q31 - q33. Abstract]Mapping of new quantitative trait loci (QTL) resistance to malaria in mice by a comparative mapping approach of human chromosome 5 q31 - q33. Abstract
Iraqi, F.A.Hernández Valladares, M.Ogugo, M.Njoroge, T.Nthale, J.King, R.Naessens, JanGibson, P.J.Musoke, A.J.Ole-MoiYoi, O.K.[Fine mapping of quantitative trait loci resistance to malaria using advanced intercross lines of mice]Fine mapping of quantitative trait loci resistance to malaria using advanced intercross lines of mice
Hernández Valladares, M.Ogugo, M.Njoroge, T.Nthale, J.Naessens, JanGibson, P.J.Musoke, A.J.Ole-MoiYoi, O.K.Iraqi, F.A.[High resolution mapping of the quantitative trait loci resistance to malaria using advanced intercross lines of mice: A step towards cloning the corresponding genes]High resolution mapping of the quantitative trait loci resistance to malaria using advanced intercross lines of mice: A step towards cloning the corresponding genes

Advances in biotechnological techniques are driven by the needs of the human populations. The new techniques in biotechnology have been developed as a consequence of the integrated use of microbiology, biochemistry and chemical engineering. Some of these technologies are being employed in the der...


Masake, R.A.Musoke, A.J.Ole-MoiYoi, O.K.[Application of biotechnology in disease diagnosis and vaccine Development]Application of biotechnology in disease diagnosis and vaccine Development
Conrad, P.A.Brown, W.C.Baldwin, C.L.Iams, K.P.Dolan, T.T.Sohanpal, B.K.Stagg, D.A.Young, A.S.Grootenhuis, J.G.Leitch, B.L.Ole-MoiYoi, O.K.[Application of DNA probes in the characterization of theilerial parasites from cattle and African buffalo]Application of DNA probes in the characterization of theilerial parasites from cattle and African buffalo

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