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Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply modifications in dendritic cytoskeleton. Rho GTPases are regulators of ac...


García-Rojo, G.Fresno, C.Vilches, N.Díaz-Véliz, G.Mora, S.Aguayo, F.Pacheco, A.Parra-Fiedler, N.Parra, C.S.Rojas, P.S.Tejos, M.Aliaga, E.Fiedler, J.L.[The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus]The ROCK inhibitor Fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic spine loss in rat hippocampus

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