An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for vaccination. While vaccination of cattle in some regions ...
Hemmink, J.D.
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Weir, W.
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MacHugh, Niall D.
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Graham, S.P.
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Patel, Ekta
,
Paxton, E.
,
Shiels, B.
,
Toye, Philip G.
,
Morrison, W. Ivan
,
Pelle, Roger
,
[Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva]
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Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva
The current Infection and Treatment Method of vaccination against East Coast fever comprises an inoculation of live Theileria parva sporozoites and simultaneous administration of oxytetracycline. Immunization with a combination of parasite types has been shown to provide broader protection than i...
Patel, Ekta
,
Lubembe, D.M.
,
Gachanja, J.
,
Mwaura, S.
,
Spooner, P.R.
,
Toye, Philip G.
,
[Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity]
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Molecular characterization of live Theileria parva sporozoite vaccine stabilates reveals extensive genotypic diversity
Patel, Ekta
,
Mwaura, Stephen
,
Giulio, Giuseppe di
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Cook, Elizabeth A.J.
,
Lynen, Godelieve
,
Toye, Philip G.
,
[Infection and treatment method (ITM) vaccine against East Coast fever: Reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine]
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Infection and treatment method (ITM) vaccine against East Coast fever: Reducing the number of doses per straw for use in smallholder dairy herds by thawing, diluting and refreezing already packaged vaccine
The Infection and Treatment Method (ITM) of vaccination against the apicomplexan parasite Theileria parva has been used since the early 1970s and is still the only commercially available vaccine to combat the fatal bovine disease, East Coast fever (ECF). The disease is tick-transmitted and result...
Patel, Ekta
,
Mwaura, S.
,
Kiara, Henry K.
,
Morzaria, S.P.
,
Peters, A.
,
Toye, Philip G.
,
[Production and dose determination of the Infection and Treatment Method (ITM) Muguga cocktail vaccine used to control East Coast fever in cattle]
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Production and dose determination of the Infection and Treatment Method (ITM) Muguga cocktail vaccine used to control East Coast fever in cattle